薄荷水质量控制方法的研究  

Quality control method of peppermint water

作　　者：陈旭[1] 楼永明[2] 黄爱文[1] 宋洪涛[1] 

机构地区：[1]南京军区福州总医院药学科,福建福州350025 [2]福建省药品检验所,福建福州350001

出　　处：《药学实践杂志》2015年第3期255-257,共3页Journal of Pharmaceutical Practice

基　　金：军队医疗机构制剂标准提高科研专项重点课题(13ZJ01)

摘　　要：目的：完善薄荷水的质量控制方法。方法采用薄层色谱法鉴别薄荷水中的薄荷素油，用气相色谱法测定薄荷水中薄荷脑的含量。结果薄层色谱法鉴别专属性强；气相色谱法中，薄荷脑线性范围为5．0∽80．0μg／ml（r＝0．9999），平均回收率为103．16％，RSD为1．81％。结论该法操作简便，结果准确，灵敏度高，重复性好，可有效地控制薄荷水的质量。Objective To consummate a method of quality control of peppermint water .Methods Thin layer chromatog-raphy was used for the identification of peppermint oil .Gas chromatography was used for the determination of mentholum . Results The identification of peppermint oil was highly specific by TLC .The linear range of mentholum was from 5 .0-80 .0 μg/ml ,r=0 .999 9 .The average recovery of mentholum was 103 .16% and RSD was 1 .81% .Conclusion These methods were easy to operate with accurate results ,which washigh sensitivity andgoodrepeatability .This quality standard could effective-ly control the quality of peppermint water .

关 键 词：薄荷水 质量控制 薄层色谱法 气相色谱法 薄荷脑 

分 类 号：R927[医药卫生—药学]