代谢综合征中医证型与危险因素关系的临床研究  

Clinical study on relationship between Chinese medicine syndrome patterns of metabolic syndrome and risk factors

作　　者：杨宇峰[1] 石岩[1] 

机构地区：[1]辽宁中医药大学,沈阳110032

出　　处：《中华中医药杂志》2015年第6期2041-2043,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家科技部"十一五"国家科技支撑计划(No.2007BAI20B103)~~

摘　　要：目的:观察代谢综合征(MS)中医气滞湿阻证和脾肾气虚证相关危险因素。方法:将北京、山东、辽宁等地符合西医及中医证型诊断的MS患者283例,收集年龄、性别、体质量指数(BMI)、腰围(WC)、收缩压(SBP)、舒张压(DBP)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、空腹血糖(FPG)、餐后2h血糖(2h PG,PBG)、糖化血红蛋白(Hb A1c)等主要指标进行分析。结果:1气滞湿阻证(13例)组BMI、WC高于脾肾气虚证组(144例,P<0.05);2脾肾气虚证组的FBG、PBG、Hb A1c高于气滞湿阻证组(P<0.05);3脾肾气虚证组的血压高于气滞湿阻证组(P<0.05);4气滞湿阻证患者的TG、LDL高于脾肾气虚证组(P<0.05)。结论:BMI、WC、TG、LDL是气滞湿阻证MS的危险因素,FBG、PBG、血压是脾肾气虚证MS的危险因素,这些规律为中医辨证治疗MS提供了理论和临床基础。Objective： To observe syndrome patterns of Chinese medicine and risk factors with combination of qi stagnation and dampness and spleen and kidney qi deficiency. Methods： The clinical study was conducted in 283 patients with MS from Beijing, Shandong and Liaoning province. The following indexes were observed, including ages, gender, BMI, WC, SBP, DBP, TC, TG, HDL, LDL, FlaG, PBG, 2hPG, HbAlc. Results： （1） BMI and WC in qi stagnation and dampness group were higher than spleen and kidney qi deficiency group （P〈0.05）. （2） FBG, PBG and HbAlc in spleen and kidney qi deficiency group were higher than spleen and kidney qi deficiency group （P〈0.05）. （3） SBP and DBP in spleen and kidney qi deficiency group were higher than qi stagnation and dampness group （P〈0.05）. （4） TG and LDL in qi stagnation and dampness group were higher than spleen and kidney Qi deficiency group （P〈0.05）. Conclusion： BMI, WC, TG and LDL are risk factors in qi stagnation and dampness, and FBG, PBG, SBP, DBP are risk factors in spleen and kidney qi deficiency. The rules cold provide a basis for treatment of MS based on syndrome differentiation.

关 键 词：代谢综合征 中医证型 临床研究 

分 类 号：R259[医药卫生—中西医结合]