慢性阻塞性肺疾病急性期不同中医证型相关指标的比较及临床意义  

Comparison and Clinical Significance of Chronic Obstructive Pulmonary Disease of Syndrome Type Related indicators

作　　者：李勇[1] 黄振炎[1] 卢育明[1] 龙文英[1] 

机构地区：[1]广东省中山市中医院内三科,广东中山528400

出　　处：《中国医药指南》2015年第16期10-11,共2页Guide of China Medicine

摘　　要：目的观察慢性阻塞性肺疾病急性发作期(AECOPD)的不同中医证型的各实验室指标(血常规、C反应蛋白、血浆D-二聚体、血气)的比较。方法通过慢性阻塞性肺疾病急性发作期患者按中医证候分型,分为痰热郁肺、痰浊阻肺、肺肾气虚、阳虚水泛、痰蒙神窍等5型,分别对比各证型患者在治疗前血常规、C反应蛋白、血浆D-二聚体、血气的水平,通过对比分析其临床意义。结果 AECOPD患者主要有痰热郁肺、痰浊阻肺和肺肾气虚三型,其中痰热郁肺患者的C反应蛋白、血浆D-二聚体、动脉血二氧化碳水平高于痰浊阻肺型,而痰浊阻型又高于肺肾气虚型,结果有统计学意义(P<0.05)。结论慢性阻塞性肺疾病急性发作期主要表现为痰热郁肺、痰浊阻肺和肺肾气虚三种证型,痰热郁肺型患者的C反应蛋白、血浆D-二聚体、动脉血二氧化碳水平均高于其他两型患者,表明痰热郁肺型患者的炎性反应明显,更易引起高凝及二氧化碳的潴留。Objective Acute phase of chronic obstructive pulmonary disease （AECOPD） of different TCM syndrome types of the laboratory indexes （routine blood, c-reactive protein and plasma D-dimer, blood gas） comparison. Methods By chronic obstructive pulmonary disease in patients with acute phase according to the TCM syndrome classiifcation, divided into phlegm yu lung heat, phlegm turbidity resistance lung, lung and kidney deifciency, Yang deifciency water lfooding, phlegm and ifve type of god and the oriifces, respectively compared to the different type patients before treatment of routine blood, c-reactive protein and the level of plasma D-dimer, blood gas, through the analysis of clinical signiifcance. Results AECOPD patients mainly have phlegm yu lung heat, phlegm turbidity resistance type lung and lung and kidney deifciency, phlegm heat depression in patients with lung of c-reactive protein, plasma D-dimer, arterial blood carbon dioxide levels higher than the lung phlegm turbidity resistance type, type and phlegm turbidity resistance is higher than that of lung and kidney deifciency type, the result was statistically signiifcant （P〈0.05）. Conclusion Chronic obstructive pulmonary disease in acute attack period mainly for phlegm yu lung heat, phlegm turbidity resistance lung and lung and kidney deifciency syndrome, phlegm heat depressive patients with type of plasma D-dimer, c-reactive protein and blood carbon dioxide levels are higher than other two patients, showed that phlegm heat type yu lung inlfammation in patients with obvious, are more likely to cause high condensation and carbon dioxide retention.

关 键 词：慢性阻塞性肺疾病 中医证型 比较 

分 类 号：R563.1[医药卫生—呼吸系统]