不同止血材料在功能性鼻内镜手术中填塞的效果:组织相容性比较  

Packing effects of different hemostatic materials during functional endoscopic sinus surgery:histocompatibility comparison

作　　者：郭丽萍[1] 王东[2] 李同丽[2] 

机构地区：[1]山西省寿阳县人民医院耳鼻喉科,山西省晋中市045400 [2]山西省人民医院耳鼻喉头颈外科,山西省太原市036200

出　　处：《中国组织工程研究》2015年第16期2588-2592,共5页Chinese Journal of Tissue Engineering Research

基　　金：山西省寿阳县人民医院耳鼻喉科;山西省人民医院耳鼻喉头颈外科的大力支持

摘　　要：背景:目前临床最常见且止血效果较好的材料为可吸收性止血棉和凡士林纱条。目的:对比可吸收性止血棉和凡士林纱条在功能性鼻内镜手术中的填塞效果。方法:纳入100例鼻窦炎患者,其中男57例,女43例,年龄16-61岁,病程5个月-23年,采用随机数表法均分为2组,观察组在功能性内镜手术治疗中采用可吸收性止血棉填塞术腔,对照组在功能性内镜手术治疗中采用凡士林纱条填塞术腔。对比两组填塞期的不适感、术后48 h抽出填塞物时的出血情况及术后24 h内的鼻腔渗血情况。结果与结论:观察组未发生与可吸收性止血棉相关的不良反应,说明可吸收性止血棉具有较高的组织相容性。观察组患者的不适反应率、术后48 h抽出填塞物时的出血率及术后24 h的鼻腔渗血量均显著低于对照组(P<0.05)。表明可吸收性止血棉具有较好的止血功能,能有效减少鼻窦炎患者术后鼻腔出血量,缓解术后不适感。BACKGROUND： At present, the most common materials for clinical hemostasis are absorbable tampons and Vaseline gauze. OBJECTIVE： To compare the packing effects of absorbable tampons and Vaseline gauze in functional endoscopic sinus surgery. METHODS： Totally 100 sinusitis patients, 57 males and 43 females, aged 16-61 years, with a history of 5 months to 23 years, were randomized into two groups： patients in the observation group were treated with absorbable tampons and patients in the control group treated with Vaseline gauze during functional endoscopic sinus surgery Patient＇s discomfort, bleeding when the filler was extracted at 48 hours, and nasal bleeding within postoperative 24 hours were compared between the two groups. RESULTS AND CONCLUSION： No adverse reaction related to absorbable tampons occurred in the observation group, indicating that the absorbable tampon has better histocompatibility. Patient＇s discomfort, bleeding when the filler was extracted at 48 hours after operation, and nasal bleeding within postoperative 24 hours were significantly improved in the observation group compared with the control group （P 〈 0.05）. These findings suggest that the absorbable tampons has a better hemostatic function, which can effectively reduce postoperative nasal bleeding and relieve postoperative discomfort in patients with sinusitis.

关 键 词：生物相容性材料 止血 内窥镜 鼻窦炎 生物材料 材料相容性 可吸收性止血棉 凡士林纱条 鼻内镜手术 止血效果 

分 类 号：R318[医药卫生—生物医学工程]