鼓室注射地塞米松治疗伴BPPV的中重度以上突发性聋疗效  

The efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV

作　　者：周晓娓[1] 虞幼军[1] 赵远新[1] 王跃建[1] 刘振[1] 刘秋玲[1] 

机构地区：[1]佛山市第一人民医院耳鼻咽喉头颈外科广东省听觉与平衡医学工程技术中心,广东佛山528000

出　　处：《临床耳鼻咽喉头颈外科杂志》2015年第10期934-936,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:研究鼓室注射地塞米松治疗伴良性阵发性位置性眩晕(BPPV)的中重度突发性聋的疗效;方法:将63例伴BPPV的中重度突发性聋分为鼓室注药初始组(A组)、全身激素给药组(B组)和鼓室注药挽救组(C组),3组同时辅以全身常规药物治疗。结果:A、B、C 3组患者的听力改善总有效率分别为60.0%、38.9%和48.0%。3组患者听力恢复的有效率均差异无统计学意义(P>0.05),但A组分别与B组、C组之间均差异有统计学意义(P<0.05)。而B组与C组之间差异无统计学意义(P>0.05)。结论:对于伴发BPPV的中重度突发性聋患者,建议初始治疗即采用鼓室注射地塞米松。Objective：To evaluate the efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV. Method： A total of 63 patients diagnosed with sudden sensorineural hearing loss with BPPV were treated through OPD. Patients were divided into three groups ： 20 cases in intratympanic dexamethasone injection as initial treatment （group A）;18 cases in systemic hormone therapy group （groupB） 25 cases in intratympanic dexamethasone injection as salvage treatment （group C）. In addition, routine drugs were used to all patients. Result：The overall effective rate of group A, B and C in hearing recovery was 60.0% 38.9 and 48.0%, respectively： ①No significant difference of hearing recovery was observed among three groups（P〉0.05） ;②A significant difference of hearing recovery was evidenced between group A and C（P〈0.05） ③A signif- icant difference of hearing recovery was evidenced between group A and C（P〈0.05） ;④No statistically significant difference was found in the hearing recovery between group B and C（P〉0.05）. Conclusion： Our data showed that intratympanic dexamethasone should be used as initial therapy for treating the moderate and severe sudden deaf- ness with BPPV.

关 键 词：聋 突发性 良性阵发性位置性眩晕 鼓室注射地塞米松 

分 类 号：R764.3[医药卫生—耳鼻咽喉科]