组织工程气管再生的研究进展  

Research Progress of Tissue-engineered Trachea Regeneration

作　　者：张思泉 仲崇浩 史宏灿 

机构地区：[1]扬州大学临床医学院胸心外科 [2]扬州大学转化医学研究中心,江苏扬州225001

出　　处：《中国胸心血管外科临床杂志》2015年第3期257-260,共4页Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

基　　金：国家自然科学基金资助项目(81370118;81170014)~~

摘　　要：组织工程气管移植成功已有报道,脱细胞气管支架的制备技术基本成熟,气管移植过程中上皮、软骨及血管再生问题就显得尤为重要。随着各种获取和培养细胞的方法及促细胞生长分化的因子研究日趋成熟,使用组织工程技术实现气管的上皮、软骨及血管再生成为可能,解决气管的上皮、软骨及血管再生具有重要的临床价值。本文就组织工程气管移植过程中上皮、软骨及血管再生情况及未来前景进行综述。Tissue-engineered tracheal transplantation has been reported and the technique of decellularized scaffold’s preparation is mature. Regeneration of epithelium, cartilage and blood vessel is particularly important during tracheal transplantation. With the increasing improvement on cell acquisition and cell culture, as well as the factor of auxesis and cell differentiation, tissue-engineered technique provided possibility and clinical value for regeneration of epithelium, cartilage and blood vessel. This review focuses on the improvement and prospect of regeneration of epithelium, cartilage and blood vessel during tracheal transplantation.

关 键 词：组织工程 气管移植 血管再生 上皮再生 软骨再生 

分 类 号：R653[医药卫生—外科学] R318.0[医药卫生—临床医学]