石墨烯夹心式聚中性红修饰电极电催化氧化多巴胺的研究  

Electrocatalytic oxidation of dopamine at poly(neutral red)/graphene-sandwiched modified electrode

作　　者：王珍珍[1] 周跃明[2,1] 梁喜珍[2,1] 丁忙 邹洪斌[1] 

机构地区：[1]东华理工大学化学生物与材料科学学院,南昌330013 [2]东华理工大学放射性地质与勘探技术国防重点学科实验室,南昌330013

出　　处：《分析试验室》2015年第6期663-666,共4页Chinese Journal of Analysis Laboratory

基　　金：放射性地质与勘探技术国防重点学科实验室开放基金项目(REGT1213;RGET1410)资助

摘　　要：用滴涂法和两步电化学聚合法制备了一种石墨烯夹心式聚中性红修饰电极（PNR/GN/GCE）,并用循环伏安法、微分脉冲伏安法和交流阻抗法表征了该复合物膜的电化学行为。石墨烯夹心式聚中性红复合物薄膜提高了电极表面的电子转移速率,薄膜结合牢固,电催化氧化作用明显。在p H 5的磷酸缓冲溶液中,选择扫速0.1 V/s,多巴胺的氧化峰电位相比裸玻碳电极负移了103 m V,峰电流增加7倍,检出限达到4.9×10^-9mol/L（S/N=3）,氧化峰电流与多巴胺浓度在1.6×10^-8~2.0×10^-6mol/L范围内现良好的线性关系,相关系数R=0.994。A novel poly （neutral red）/graphene-sandwiched modified glassy carbon electrode （PNR/GN/GCE） was fabricated by drop-coating and two-step electrochemical polymerization. Its electrochemical behaviors were investigated by cyclic voltammetry （CV）, differential pulse voltammetry （DPV） and electrochemical impedance spectroscopy （EIS）. The experimental results showed that electrocatalytic oxidation of dopamine （DA） could be improved bythe PNR/GN-sandwiched composite film with high electron transfer rate and firmness. Peak potential of DA oxidation was shifted negatively by 103 mV in phosphate buffer solution （pH 5. 0 ） at scan rate of 0.1 V/sand the peak current was increased by 7. 4 fold compared with that of a bare electrode. The DA calibration curve was linearin a wide concentration range of 1.6 ×10^ -8 - 2.0 × 10 ^-6moL/L with a detection limit of 4.9 × 10 ^-9 mol/L （ S/N= 3 ）. The simply fabricated electrode was stable enough to be applied to direct detection of DA inurine.

关 键 词：石墨烯夹心式 聚中性红 化学修饰电极 多巴胺 电催化氧化 

分 类 号：O657.1[理学—分析化学]