基于芳香分子-糖类手性超分子组装体及功能  

Chiral Supramolecular Assemblies Based on Aromatic Molecules-Carbohydrate Conjugates and Their Applications

作　　者：王克让[1,2] 

机构地区：[1]河北省化学生物学重点实验室河北大学化学与环境科学学院,保定071002 [2]药物化学与分子诊断教育部重点实验室,保定071002

出　　处：《化学进展》2015年第6期775-784,共10页Progress in Chemistry

基　　金：国家自然科学基金项目(No.21372059);河北省教育厅优秀青年基金项目(No.YQ2013006)资助~~

摘　　要：手性超分子组装体广泛存在于自然界中,因其在材料、化学和生物学等领域广阔的应用前景,引起了科学家们极大的兴趣。其中以糖类分子作为手性源,经分子自组装构筑手性超分子组装体的研究已成为超分子化学领域的研究热点之一。本文综述了基于糖类修饰的苝酰亚胺分子、偶氮苯分子、联苯类分子和卟啉类分子等芳香分子化合物经自组装构筑的手性超分子组装体,介绍了其在有机溶剂和水的混合溶剂、水中的凝胶性质,超分子手性特征和功能,糖分子类型与超分子组装体手性间的关系等,并对基于糖类的手性超分子组装体的前景进行了展望。In nature, helical self-assembly by non-covalent interactions is a widely observed feature. Inspired by the unique features of fascinating chiral superstructures, chemists have paid more attention to design numerous helical supramolecular assemblies. In them, carbohydrates as a natural source of chirality have been widely investigated in the construction of chiral supramolecular assembly, which possessed potential application in materials, chemistry and biology. This review aims to overview of the chiral supramolecular assembly based on aromatic molecules-carbohydrate conjugates, including perylene bisimides, azobenzene, poly （p-phenylene） , porphyrins, and so on. Their gel properties, supramolecular chirality and functionalization in the mixtures of organic solution and water, or in water, and the relationship between their supramolecular chirality and the type of the carbohydrates are described. Furthermore, the potential application and future development of the chiral supramolecular assembly based on carbohydrates are discussed.

关 键 词：手性 超分子组装体 糖类 自组装 苝酰亚胺 

分 类 号：O641.3[理学—物理化学] O629.13[理学—化学]