我院门诊输液区137例患儿静脉滴注给药致不良反应报告分析  

Analysis of 137 Cases of Pediatric Adverse Drug Reaction by Intravenous Infusion in Transfusion Area of Outpatient Department in Our Hospital

作　　者：何珊 常宏[1] 赵雅妮 

机构地区：[1]南方医科大学附属深圳市妇幼保健院,广东深圳518028

出　　处：《中国药房》2015年第17期2359-2361,共3页China Pharmacy

摘　　要：目的：了解我院门诊输液区患儿静脉滴注给药致药品不良反应（ADR）发生的规律及特点,为临床合理运用静脉滴注治疗提供参考。方法：收集我院2013年12月-2014年11月门诊输液区发生并上报的137例儿童静脉滴注给药致ADR报告并进行统计、分析。结果：137例ADR报告中,原患疾病全部为感染性疾病;男性、女性患儿报告数差异无统计学意义（P=0.073）;4-6岁组报告的例数最多（占45.99%）;ADR多发于1 d内的后12个h;春季是儿童ADR的高发季节（占45.25%）;抗菌药物引起的ADR发生率最高（占75.50%）;患儿ADR以皮肤及其附件最常见（占90.51%）;有22例新的一般的ADR报告。结论：临床在给予患儿静脉滴注用药时,应充分考虑其与成人的差异产生的药物作用的独特性,并跟踪患儿用药反应,切实减少ADR的发生。OBJECTIVE： To study the regularity and the characteristics of pediatric ADR by intravenous infusion in transfusion area of outpatient department in our hospital, promote the rational drug use and improve the awareness of medical staff about the pediatric ADR monitoring. METHODS： 137 cases of pediatric ADR reported in transfusion area of outpatient department from Dec. 2013 to Nov. 2014 were collected and statistically analyzed. RESULTS： Among the 137 cases, the primary disease was infectious disease; male case was more than female （P=0.073）, children aged 4-6 years old occupied the highest proportion （45.99%）, ADR mainly occurred in the last 12 h in a day and ADR cases occupied the highest proportion in spring （45.25%） ; ADR cases caused by antibiotics stood the highest （75.50%） ; the main clinical manifestations of ADR cases were the lesions of skin and its appendants, mainly allergic reaction （90.51%）; there were 22 new types of ADR cases. CONCLU- SIONS. The specificity of drug interaction due to the difference from the adult should be considered when the children are given intravenous infusion reduce the incidence of ADR.

关 键 词：药品不良反应 儿童 合理用药 静脉滴注 

分 类 号：R969.3[医药卫生—药理学]