北京地区胎龄别新生儿出生头围分析  

Percentile curves for gestational age-specific head circumference of newborns in Beijing

作　　者：贾朝霞[1] 宋培歌[2] 王军华[1] 赵永鲜[1] 潘迎[1] 庞汝彦[2] 武明辉[1] 

机构地区：[1]首都医科大学附属北京妇产医院,北京100026 [2]北京大学公共卫生学院妇女与儿童青少年卫生学系,北京100191

出　　处：《中国儿童保健杂志》2015年第6期580-583,共4页Chinese Journal of Child Health Care

基　　金：比尔梅琳达.盖茨基金会"21世纪胎儿与新生儿生长发育标准研究"(MREC N°:08/H0606/139;UKCRN ID:8454)

摘　　要：目的建立以人群为基础的胎龄别新生儿出生头围百分位数修匀曲线。方法采用横断面调查的方法对北京市顺义区医院及顺义区妇幼保健院2009年11月1日-2011年1月21日间出生的新生儿进行体格指标的标准化测量,并进行严格的质量控制。采用偏度-中位数-变异系数法（LMS）对不同胎龄新生儿出生头围百分位数进行修匀,得到修匀后的参考曲线,并与1986-1987年中国15市新生儿体格发育调查结果进行比较。结果共5 201例符合标准的研究对象纳入分析,获得了顺义区新生儿胎龄别出生头围的修匀曲线。37～41周的胎龄别出生头围,男婴比女婴的头围大0.3～0.4cm,差异具统计学意义（P〈0.05）。本研究测得的胎龄别出生头围均低于1986-1987年中国15市新生儿体格发育调查结果。结论本研究建立了北京市顺义区胎龄别新生儿出生头围百分位数修匀长曲线,为该地区及其它类似地区评估胎儿生长发育提供了较新的参考依据。Objective To establish population-based percentile curves for gestational-age specific head circumference of newborns. Methods Data were collected from November 1st 2009 to January 21st 2011 in Shunyi District Hospital of Beijing and Shunyi Maternal and Child Health Hospital. All newborns who were born in these two hospitals were taken standard physical measurements. Strict quality control was essential for assurance of the quality of data. LMS program was used to smooth the percentile curve. And the results with investigation results of 15 cities of China in 1986-1987 were also com- pared. Results A total of 5 201 subjects were engaged. Percentiles at P3, P10, P25, Pa0, PTs, P90, P97 of head circumference were calculated, and the corresponding rderence curves for gestational age-specific and gender-specific were successfully smoothed. Differences of head circumference between boys and girls were significant at 37-41 weeks, head circumference values were higher in boys. But our measurements were lower than the investigation results of 15 cities of China in 1986- 1987. Conclusion Gestational age-specific and gender-specific percentiles are presented in this study. And it would be proposed a current reference for the loeal clinicians and researchers to evaluate fetal growth.

关 键 词：新生儿 胎龄别头围 修匀百分位数 

分 类 号：R723[医药卫生—儿科]