红细胞分布宽度在慢性心力衰竭患者预后评估中的意义  

The significance of prognosis evaluation of red cell distribution width in patients with chronic heart failure

作　　者：翟英慧[1] 郝咏刚[2] 李海涛[1] 

机构地区：[1]Department of Cardiology, Beijing Puren Hospital [2]Department of Neurology, Beijing Chaoyang Hospital Affiliated to Capital Medical University

出　　处：《中华临床医师杂志（电子版）》2015年第9期15-18,共4页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：目的探讨慢性心力衰竭患者红细胞分布宽度(RDW)与心功能的关系及其对预后评估的意义。方法选取152例慢性心力衰竭患者,随访2年。(1)按照入院时的心功能水平将患者分为3组(NYHAⅡ、Ⅲ、Ⅳ级),分别进行RDW、NT-pro BNP、LVEF、LVDd的比较;(2)根据入院时患者的RDW水平分为2组(正常组、增高组),分别进行NT-pro BNP、LVEF、LVDd、恶性心律失常发生率、2年死亡率的比较;(3)根据随访结束时患者的转归分为存活组和死亡组,分别比较RDW、NT-pro BNP、LVEF、LVDd、恶性心律失常发生率。结果 (1)不同心功能分级的慢性心力衰竭患者RDW、NT-pro BNP、LVDd、LVEF间差异有统计学意义(P<0.05)。(2)不同RDW水平患者NT-pro BNP、LVDd、LVEF、发生恶性心律失常事件、2年死亡率比较,差异均有统计学意义(P<0.05)。(3)死亡组与存活组在RDW、NT-pro BNP、LVEF方面比较,差异有统计学意义(P<0.05)。结论在慢性心力衰竭患者RDW与心功能密切相关,为预后的评估提供了新的方法。Objective To investigate the relationship between red cell distribution width （RDW） and cardiac function class and to predict the prognosis in patients with chronic heart failure. Methods 152 cases of chronic heart failure were followed up for 2 years. （1）According to cardiac function class, the patients were divided into 3 groups （NYHAⅡ, Ⅲ, Ⅳ）, RDW, NT-proBNP, LVEF, LVDd were compared between the 3 groups. （2）According to RDW levels, the patients were divided into 2 groups （normal and high）, NT-proBNP, LVEF, LVDd, fatal arrhythmia occurrence, death rate were respectively compared. （3）According to the outcomes, the patients were divided into survival group and death group, RDW, NT-proBNP, LVEF, LVDd and the incidence of fatal arrhythmia were respectively compared. Results （1）There was statistically significant difference between different classification of cardiac function in RDW, NT-proBNP, LVDd, LVEF （P〈0.05）. （2）There was statistically significant difference between 2 RDW levels in NT-proBNP, LVDd, LVEF, the occurrence of fatal arrhythmia and prognosis （P〈0.05）. （3） RDW, NT-proBNP, LVEF in death group compared with survival group, the difference is statistically significant （P〈0.05）. Conclusion In patients with chronic heart failure, RDW was closely related with cardiac function, it maybe provide a new method for the evaluation of prognosis.

关 键 词：心力衰竭 预后 红细胞分布宽度 

分 类 号：R541.6[医药卫生—心血管疾病]