β-受体阻滞剂干预更年期妇女心电图变化的临床价值  

Clinical significance of beta-receptor blocker intervention on ECG changes in climacteric women

作　　者：贺桦 李针[2] 渠红霞 孟凡琳 王兵 

机构地区：[1]总装备部无锡疗养院,江苏无锡214063 [2]解放军第一一三医院肝病急诊科

出　　处：《海军医学杂志》2015年第3期218-220,共3页Journal of Navy Medicine

摘　　要：目的探讨β-受体阻滞剂干预更年期妇女心电图变化的临床价值。方法选取无器质性疾病但有心电图改变的更年期妇女62例,经患者知情同意按照数字表法随机分为治疗组31例,予以β-受体阻滞剂治疗3周;另31例为对照组,不给予任何治疗。观察治疗前后2组间及治疗组心电图指标(心率、心律、ST-T)的改变。结果 (1)经β-受体阻滞剂治疗3周后,2组平均心率、心律、ST-T改变(除ST上斜外)比较差异均有统计学意义(P<0.05)。(2)治疗组治疗前后比较,成对房早、ST上斜和T波倒置虽有改变,但差异无统计学意义(P>0.05);其余指标均有明显改变,差异有统计学意义(P<0.05)。结论β-受体阻滞剂应用于心电图改变的更年期妇女有一定的临床价值。Objective To investigate the clinical significance of beta-receptor blocker intervention on ECG changes in climacteric women. Methods Sixty-two subjects of climacteric women without organic diseases but with ECG changes were chosen and randomly divided into 2 groups ： the control group （ n = 32） and the treatment group （ n = 30）. The subjects of the control group were not given any treatment, while the subjects of the treatment group were given treatment of beta-receptor blocker intervention for 3 weeks. ECG changes （heart rate, rhythm and ST-T changes） were detected both before and after treatment, and then, comparisons were made between the groups and within the groups. Results （ 1 ） After 3 weeks of beta-receptor blocker intervention, significant ECG changes could be noted in heart rate, rhythm and ST-T changes （except ST cable） in the subjects of the treatment group, with statistical significance, when comparisons were made between the 2 groups （ P 〈 0.05 ）. （2） In treatment group, though changes were seen in the paired atrial premature beat （APB）, ST cable and T wave inversion, there no statistic significance, when comparisons were made between pre and post treatment （ P 〉 0. 05 ）. There were significant changes in the remaining parameters, with statistical significance （ P 〈 0.05 ）. Conclusion Beta-receptor blocker had its clinical value, when it was used in climacteric women with ECG changes.

关 键 词：Β-受体阻滞剂 更年期妇女 心电图 

分 类 号：R540.41[医药卫生—心血管疾病]