中药治疗过敏性疾病的药理作用研究进展  

Advances in pharmacologic studies on treatments of allergic diseases by Chinese materia medica

作　　者：王化龙[1,2] 李振虎[1,2] 徐砚通[1,2] 

机构地区：[1]天津中医药大学天津市现代中药重点实验室,天津300193 [2]天津国际生物医药联合研究院中药新药研发中心,天津300457

出　　处：《中草药》2015年第10期1542-1555,共14页Chinese Traditional and Herbal Drugs

基　　金：国家科技重大专项(2013ZX09201020);天津市应用基础及前沿技术研究计划项目(12JCYBJC32400);科技部国家国际合作专项(2013DFA31620)

摘　　要：中药治疗过敏性疾病临床疗效确切,但其活性成分和作用机制尚在探索中。总结了近年来中药复方、单味中药提取物和中药活性成分在治疗过敏性疾病方面的药理作用研究进展,突出体现了中药抗过敏作用具有多成分、多靶点和多途径特征,从而加深对中药抗过敏作用的认识,一方面为中药治疗过敏性疾病的临床应用提供参考,另一方面为研发抗过敏中药产品提供信息。Clinical evidences demonstrated the effects of Chinese materia medica （CMM） on allergic diseases. However, the bioactive components in CMM and their mechanims of actions remain unkown. The progress of pharmacological studies on the anti-alleric effects of multi-herb formulation, herbal extracts/fraction, and pure compounds of CMM was summerized, which showed the characteristics of multi-component, multi-target, and multi-mechanism of CMM effects. This review provides the information for clinical use of anti-allergic CMM and drug discovery of anti-allergic CMM products.

关 键 词：中药 复方 单味中药 活性成分 过敏性疾病 抗过敏 

分 类 号：R285[医药卫生—中药学]