Structure of Copper Chelate of 2-Hydroxy-4-methylthiobutanoic Acid as Trace Mineral Additive in Animal Feeding  

作　　者：杨再文 阿依古丽纳曼 刘向荣 赵顺省 赵玮钦 杨水兰 

机构地区：[1]College of Chemistry and Chemical Engineering,Xi'an University of Science and Technology

出　　处：《Chinese Journal of Structural Chemistry》2015年第1期147-153,共7页结构化学（英文）

基　　金：supported by the National Natural Science Foundation of China (No. 21301139,21373158,21103135,51304158);Scientific Research Program Funded by Shaanxi Provincial Education Department (No. 2013JK0651);the Scientific Research Cultivating Fund (No. 201221);the Doctoral Starting Fund (No. 2014QDJ004) from Xi'an University of Science and Technology

摘　　要：The chelate complex of Cu2＋ with 2-hydroxy-（4-methylthio）butanoate（MHA-H, the anion derived from the so-called methionine hydroxy-analogue, largely used in animal nutrition as a source of methionine, MHA） is an efficient, bioavailable trace mineral additive for animal feeding. The structure of MHA-H copper chelate was investigated by single-crystal X-ray diffraction. The crystal structure（C10H18Cu O6S2, 1, monoclinic, space group P21/c, Z = 2, a = 16.158（4）, b = 4.9733（12）, c = 9.159（2） ？, β = 104.786（4）°） exhibits that two MHA-H ligands coordinate with a CuII ion to form a square-planar environment completed to an octahedron through interaction with carbonyl oxygens of neighboring molecules, which expand to constitute a two-dimensional sheet coordination network. And a separation between the hydrophilic and lipophilic moieties like micelles was found in the packing structure. X-ray powder diffraction and thermogravimetric analysis were used to study the phase purity of the bulk sample and thermostability of complex 1, respectively.The chelate complex of Cu2＋ with 2-hydroxy-（4-methylthio）butanoate（MHA-H, the anion derived from the so-called methionine hydroxy-analogue, largely used in animal nutrition as a source of methionine, MHA） is an efficient, bioavailable trace mineral additive for animal feeding. The structure of MHA-H copper chelate was investigated by single-crystal X-ray diffraction. The crystal structure（C10H18Cu O6S2, 1, monoclinic, space group P21/c, Z = 2, a = 16.158（4）, b = 4.9733（12）, c = 9.159（2） ？, β = 104.786（4）°） exhibits that two MHA-H ligands coordinate with a CuII ion to form a square-planar environment completed to an octahedron through interaction with carbonyl oxygens of neighboring molecules, which expand to constitute a two-dimensional sheet coordination network. And a separation between the hydrophilic and lipophilic moieties like micelles was found in the packing structure. X-ray powder diffraction and thermogravimetric analysis were used to study the phase purity of the bulk sample and thermostability of complex 1, respectively.

关 键 词：copper complex methionine hydroxy-analogue metal chelates for animal feeding X-ray structure 

分 类 号：S816.7[农业科学—饲料科学] O627.12[农业科学—畜牧学]