新疆地区762例上尿路结石患儿结石成分分析  

Stone composition analysis of 762 children with urinary tract stones in Xinjiang

作　　者：宋光鲁[1] 乃比江·毛拉库尔班[1] 杨凡[2] 阿斯木江·阿不拉[1] 安尼瓦尔·牙生[1] 王玉杰[1] 

机构地区：[1]新疆医科大学第一附属医院泌尿中心,乌鲁木齐830054 [2]新疆阿克苏地区新和县人民医院泌尿外科

出　　处：《中华泌尿外科杂志》2015年第6期429-432,共4页Chinese Journal of Urology

摘　　要：目的：探讨新疆地区上尿路结石患儿结石成分分布的民族、性别及年龄差异，为制定治疗方案提供依据。方法采用结石红外光谱自动分析仪对2009年12月至2013年3月入院治疗的762例患儿的上尿路结石标本进行结石成分分析，并结合临床资料进行比较。结果①762例患儿尿路结石的主要类型为含钙结石，占79．0％，男女差异无统计学意义（ P＞0．05）。②患儿年龄以0～5岁为主，占48．7％。不同年龄组患儿的性别分布差异显著，11～15岁患儿中女性占比显著高于男性患儿，其他年龄组男性占比高于女性（ P＜0．05）。③含钙结石和尿酸结石分布存在显著的民族差异（ P＜0．05）。维吾尔族患儿中含钙结石和尿酸结石的比重显著高于汉族和哈萨克族，分别为82．5％、62．1％、65．8％和51．1％、28．8％、30．4％。不同民族之间感染性结石的分布差异无统计学意义（P＞0．05）。④不同年龄组尿酸结石分布差异有统计学意义（P＜0．05），其中11～15岁患儿尿酸结石的比重显著小于其他年龄段患儿；但含钙结石和感染性结石的分布差异无统计学意义（P＞0．05）。结论新疆地区上尿路结石患儿结石成分以含钙结石为主，其次为尿酸结石，维吾尔族男性占比最高。此类患儿的治疗应以外科干预和药物溶石并重。Objective To find the differences of urinary stone composition of children in Xinjiang among different ethnics, genders and age groups and provide evidence for the treatment of those suffered children.Methods Stone IR automatic analyzer was used to analyze stone composition of upper urinary tract calculi specimens from 762 children who were hospitalized between January 2009 and March 2013, and clinical data were compared.Results The analysis of stone composition of 762 children with urinary calculi showed that： （ 1 ） Calcium stones accounted for 79.0%, far more than other types and no significant difference between genders （ P〉0.05 ） .（ 2 ） Children aged 0 to 5 years accounted for 48.7%.Gender distribution of age groups were significantly different, with female children in 11 to 15 years group accounting for 31.8%, far more than males, and males accounting for more in the other age groups （P〈0.05）.（3） There were significant ethnic differences in distribution of calcium stones and uric acid stones. The proportion of Uygur children with calcium stones and uric acid stones was significantly greater than Han and Kazak, respectively, with 82.5% versus 62.1%, 65.8% and 51.1% versus 28.8%, 30.4%. No significant difference of infection stones among ethnic groups （P〉0.05）.（4） Distribution of children with uric acid stones was significantly different （P〈0.05） among age groups, and uric acid stones in 11 to 15 age group was significantly less than that in other age groups （ 36.9% versus 50.4% and 49.3%） .The distribution of calcium stones and urinary infection was not significantly different （P〉0.05）.Conclusions Calcium stones account the highest in urinary stones in children in Xinjiang, followed by uric acid stones, and urinary calculi is more common in Uygur male children than female children.Surgical intervention and drug dissolving should be balanced for the treatment.

关 键 词：尿路结石 结石成分 红外线 

分 类 号：R726.9[医药卫生—儿科]