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作 者:孙海燕[1] 吴金英[1] 曲淑君 刘飞宇[1] 赵泉[1] 邹少华[1]
机构地区:[1]烟台毓璜顶医院,山东烟台264000 [2]烟台市烟台山医院
出 处:《药物流行病学杂志》2015年第6期361-363,共3页Chinese Journal of Pharmacoepidemiology
基 金:烟台市科技发展计划项目(编号:2012069)
摘 要:目的:调查某院血液病科2012~2013年分离细菌分布及其对抗菌药的耐药状况,为临床合理使用抗菌药提供依据。方法:对该科2012~2013年住院患者送检标本中分离得到的致病菌进行对比分析。结果:排在前三位的分别为大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌,大肠埃希菌和肺炎克雷白菌产ESBL比例分别为66.7%和32.1%,大肠埃希菌和肺炎克雷伯菌对替加环素的耐药率分别为5.8%和5.7%,凝固酶阴性葡萄球菌和金黄色葡萄球菌对苯唑西林耐药率分别为91.3%和31.6%,肺炎链球菌对青霉素的耐药率为5.0%。结论:掌握该科室的细菌分布及耐药变迁,对促进抗菌药的合理选用,减少细菌耐药性的产生具有重要意义。Objective:To advise rational using of antibiotic drugs by according to the outcome of investigating the pathogen distribution and antibiotic resistance of inpatients in hematological department from 2012 to 2013. Methods: To analyze the pathogenic bacteria separating from the samples of patents from 2012 to 2013. Results:The main strains were Escherichia coli (eco) , Klebsiella pneumonia (kpn) and Pseudornonas aeruginosa (pae) in hematological department from 2012 to 2013, the ESBL of eco and kpn was about 66.7% and 32.1%. The antibiotic resistance of eco and kpn for tigecy- cline was 5.8 % and 5.7% , respectively. The antibiotic resistance of Coagulase negative Staphylococcus and Staphylococcus aureus for oxacillin was 91.3% and 31.6%. The antibiotic resistance of Streptococcus Prteumoniae for penicillin was 5.8%. Conclusion:It is important to know the bacteria distribution and antibiotic resistance tot promoting the rationality of using antibiotic drugs and reducing antibiotic resistance.
分 类 号:R378[医药卫生—病原生物学]
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