在海南山区搜索残余疟疾病例的初步研究  

A preliminary study on searching of residual malaria cases in Hainan mountainous areas

作　　者：林明和 王善青[2] 杜建伟[2] 林理[3] 胡锡敏[2] 王光泽[2] 李雨春[2] 吴开琛[4] 

机构地区：[1]万宁市疾病预防控制中心,海南万宁571500 [2]海南省疾病预防控制中心,海南海口570203 [3]哈尔滨医科大学大庆分校,黑龙江大庆163319 [4]中国疾病预防控制中心寄生虫病预防控制所,上海200025

出　　处：《中国热带医学》2015年第5期617-618,共2页China Tropical Medicine

基　　金：海南省自然科学基金项目(No.813251)

摘　　要：目的试图在近年疟疾发病率已降至零的海南山区搜索残余疟疾病人,以检验当地疟疾发病率降至零的可靠性,为评估海南省消除疟疾的进展提供参考。方法选择海南东南部原高疟山区万宁市南桥镇以及三更罗镇的两个行政村及其邻近的南林农场和新中农场的三个作业区,以经常上山住宿的高危人群作为调查检测对象,同时采用两种检测方法,即疟疾快速诊断试验(RDT)和聚合酶链反应(PCR)进行检测。结果总共调查检测480人,PCR检测全部为阴性;RDT检测发现两例间日疟阳性反应。但经厚血膜镜检复查均为阴性,予以否定。结论调查结果从一个个侧面证实当地疟疾传播确已下降至很低的水平,对当地发病率监测结果提供了有力的支持,从而为海南省消除疟疾的评估提供了参考。Objective To search the residual malaria cases in high-risk population in mountainous areas of Wanning citywhere incidence of malaria reduced to zero and to provide reference for assessment of results of malaria elimination in Hainanprovince. Methods The high-risk villagers frequently work and sleep on mountainous areas in two administrqtve villages andthree operation areas of Nanlin state farm and Xinzhong farm in Nanqiao and Sangengluo townships previously high prevalentwih malaria in Wanning city were selected and detected by RDT and PCR for residual malaria infection. Results A total of480 villagers were investigated, all negative by PCR, and RDT assay showed two villager were positive for Plasmodium vivax,but they were negative after re-examination by microscopy and PCR. Conclusion The local malaria incidence has actuallydropped to a very low level, strongly supporting the achievement in local malaria surveillance and provide reference forevaluation of malaria elimination in Hainan province.

关 键 词：疟疾 消除 残余病例 搜索 

分 类 号：R531.3[医药卫生—内科学]