金喉健喷雾剂中大果木姜子油的定性定量测定  

Qualitative and quantitative study of Cinnamomum migao oil in Jinhoujian spray

作　　者：王俪瓯 田莉[2] 茅向军[2] 杨勇[3] 杨微微[1] 游正琴 

机构地区：[1]贵阳医学院,贵阳550004 [2]贵州省食品药品检验所,贵阳550004 [3]贵阳中医学院,贵阳550002

出　　处：《中南药学》2015年第5期528-530,共3页Central South Pharmacy

基　　金：贵州省中药现代化科技产业研究开发专项项目(No.黔科合中药字【2012】5030);贵阳市科技计划项目(No.筑科合同21012204)

摘　　要：目的建立金喉健喷雾剂中大果木姜子油的定性定量研究方法。方法对大果木姜子油中主要成分1,8-桉叶素进行薄层色谱法定性鉴别;并采用GC法测定其含量。结果 1,8-桉叶素在0.049 9~0.399 6 mg·m L-1内与峰面积呈良好的线性关系（r=0.999 8）,平均回收率为96.6%~98.5%,RSD〈1.5%（n=3）。结论所建立的方法稳定可靠,可有效控制该制剂的质量。Objective To establish the quality standard for Cinnamomum migao oil in Jinhoujian spray. Methods Thin layer chromatography （TLC） was used in qualitative identification of 1, 8-cineole. GC was used for the assay of 1, 8-cineole in the preparation. Results We detected 1, 8-cineole by TLC. Good linearity was found for 1, 8-cineole had at 0.049 9 -- 0.399 6 mg mL - 1. The average recoveries were at 96.6% -- 98.5% and the RSDs were less than 1.5% （n = 3）. Conclusion The method is stable and reliable. It can be used for the quality control of Jinhoujian spray.

关 键 词：金喉健喷雾剂 大果木姜子油 1 8-桉叶素 薄层色谱 气相色谱法 定性定量 

分 类 号：R917[医药卫生—药物分析学]