单纯氯胺酮麻醉与氯胺酮诱导后七氟醚维持麻醉在小儿疝气手术中的应用比较  

Application comparison between only ketamine anesthesia and ketamine induced sevoflurane maintain anesthesia in pediatric hernia surgery

作　　者：陆巧芸 赵新民[1] 宋正亮 岳书玉[1] 

机构地区：[1]江苏省盐城市妇幼保健院麻醉科,224002

出　　处：《临床合理用药杂志》2015年第17期32-32,41,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的比较七氟醚联合氯胺酮与单纯氯胺酮在小儿疝气麻醉中应用的麻醉效果。方法选择ASAⅠ~Ⅱ级的手术患儿60例,随机分为氯胺酮组（L组）和七氟醚组（Q组）各30例。L组予氯胺酮单纯麻醉,Q组予氯胺酮诱导后七氟醚维持麻醉。观察、记录并比较2组患儿麻醉后呼吸、心率、Sp O2、苏醒时间、呼吸道分泌物、术中躯体活动与术后躁动等情况。结果 2组术中呼吸、Sp O2比较差异无统计学意义（P〉0.05）;Q组心率、呼吸道分泌物,术中躯体活动,术后躁动状况均优于L组,差异有统计学意义（P〈0.05）。结论七氟醚联合小剂量氯胺酮在小儿疝气的麻醉中比单纯氯胺酮麻醉更有利于机体平稳,呼吸系统并发症少,不良反应少,患儿易于接受,值得临床推广应用。Objective To explore the anesthetic effect of sevoflurane joint ketamine and simple ketamine anesthesia in pediatric hernia surgery. Methods 60 cases of ASA Ⅰ ~ Ⅱ,age 0. 5 ~ 10 years old,weight 4 ~ 40 kg of hernia children were randomly divided into ketamine group（ L group） and sevoflurane group（ Q group）,each of 30 cases. The L group received simple ketamine anesthesia,while the Q group received ketamine induced sevoflurane maintain anesthesia. The respiration,heart rate,Sp O2,recovery time,respiratory tract secretion,intraoperative somatic activity and postoperative restlessness of 2groups were observed and recorded. Results There were no significant differences of intraoperative respiration,Sp O2between2 groups（ P〈0. 05）. The heart rate,respiratory tract secretion,intraoperative somatic activity and postoperative restlessness of the Q group were better than those of the L group,the differences were statistically significant（ P〈0. 05）. Conclusion Sevoflurane combined with small dose of ketamine anesthesia in pediatric hernia surgery is more stable than simple ketamine intravenous anesthesia,with less adverse reactions. So the patients are more likely to accept. It is worthy of clinical application.

关 键 词：氯胺酮 七氟醚 小儿 麻醉 

分 类 号：R726.1[医药卫生—儿科]