妇科万应膏治疗宫寒血瘀型痛经的临床效果观察  

Clinical observation of Fuke Wanyinggao in the treatment of uterine cold blood stasis type dysmenorrhea

作　　者：林佳璐 刘珠[2] 高振强[3] 庞义存[3] 

机构地区：[1]河北省保定市第五医院,071051 [2]石家庄市食品药品检验所,050031 [3]河北医科大学第三医院,石家庄市050051

出　　处：《临床合理用药杂志》2015年第17期35-36,15,共3页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的观察妇科万应膏治疗宫寒血瘀型痛经患者的疗效和安全性。方法根据纳入/排除标准,共筛选痛经患者223例,采用区组随机的方法,按照3∶1的比例随机分为试验组167例与对照组56例。试验组使用妇科万应膏外用穴位贴敷,对照组使用痛经宝颗粒口服,共用药3个月经周期。治疗后比较2组的治疗效果与不良反应。结果治疗3个月经周期后,试验组总有效率为91.02%明显优于对照组的78.57,差异有统计学意义(P<0.05)。试验组发生不良反应5例,不良反应发生率2.89%;对照组无不良反应发生,组间比较差异无统计学意义(P>0.05)。结论妇科万应膏治疗宫寒血瘀型月经不调和痛经安全有效,值得临床推广使用。Objective To observe the efficacy and safety of Fuke Wanyinggao in the treatment of uterine cold blood stasis type of dysmenorrhea patients. Methods A randomized,open, positive controlled, multi-center clinical trial design,223 cases of patients with dysmenorrhea were selected according to the ratio of 3：1 ,and randomly divided into experimental group （ 167 cases） and control group （56 cases）. The experimental group received topical acupoint application by using Fuke Wany- inggao, while the control group was given Fuke Wanyinggao granule oral medicine. Three menstrual cycles were administered. The therapeutic effect and adverse reactions of 2 groups were compared. Results After 3 menstrual cycles,the total effective rate was 91.02% in experimental group, which was higher than 78.57% of the control group, the difference was statistically significant （ P 〈 0.05 ）. There were 5 cases of adverse reactions in the experimental group, the adverse reaction rates were 2. 89%, and the control group had no adverse events. There was no significant differences between 2 groups （P 〉 0.05 ）. Conclusion Treating uterine cold blood stasis type of dysmenorrhea is safe and effective by using Fuke Wanyinggao, which is worthy of clinical use .

关 键 词：妇科万应膏 痛经宝颗粒 痛经 宫寒血瘀 

分 类 号：R271.113[医药卫生—中医妇科学]