Visible-light-driven enhanced antibacterial and biofilm elimination activity of graphitic carbon nitride by embedded Ag nanoparticles  

作　　者：Wei Bing Zhaowei Chen Hanjun Sun Peng Shi Nao Gao Jinsong Ren Xiaogang Qu 

机构地区：[1]Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Changchun, Jilin 130022, China [2]College of Life Science, Jilin University, Changchun, Jilin 130012, China

出　　处：《Nano Research》2015年第5期1648-1658,共11页纳米研究（英文版）

基　　金：This work was supported by the National Basic Research Program of China （Nos. 2011CB936004 and 2012CB720602） and the National Natural Science Foundation of China （Nos. 21210002, 21431007, 91413111, 21402183）.

摘　　要：Semiconductor nanomaterials with photocatalytic activity have potential for many applications. An effective way of promoting photocatalytic activity is depositing noble metal nanoparticles （NPs） on a semiconductor, since the noble metal NPs act as excellent electron acceptors which inhibit the quick recombination of the photoexcited electron-hole pairs and thereby enhance the generation of reactive oxygen species （ROS）. Herein, a highly effective platform, graphitic carbon nitride （g-C3N4） nanosheets with embedded Ag nanopartides （Ag/g-C3N4）, was synthesized by a facile route. Under visible light irradiation, the ROS production of Ag/g-C3N4 nanohybrids was greatly improved compared with pristine g-C3N4 nanosheets, and moreover, the nanohybrids showed enhanced antibacterial efficacy and ability to disperse bacterial biofilms. We demonstrate for the first time that the Ag/g-C3N4 nanohybrids are efficient bactericidal agents under visible light irradiation, and can also provide a new way for biofilm elimination. The enhanced antibacterial properties and biofilm-disrupting ability of Ag/g-C3N4 nanohybrids may offer many biomedical applications.有 photocatalytic 活动的半导体 nanomaterials 为许多应用有潜力。支持 photocatalytic 活动的一个有效方法在一个半导体上正在扔高贵金属 nanoparticles (NP ) ，自从 NP 作为禁止 photoexcited 电子洞对的快再结合并且从而提高反应的氧种类(ROS ) 的产生的优秀电子领受人扮演的高贵金属。此处，一个高度有效的平台， graphitic 碳氮化物( g-C <潜水艇class=“ a-plus-plus ”> 3 </sub > N <潜水艇class=“ a-plus-plus ”>有嵌入的 Ag nanoparticles 的 4 </sub>) nanosheets ( Ag/g-C <潜水艇class=“ a-plus-plus ”> 3 </sub > N <潜水艇class=“ a-plus-plus ”> 4 </sub>),被综合由一灵巧的线路。在可见轻照耀下面， Ag/g-C 的 ROS 生产<潜水艇class=“ a-plus-plus ”> 3 </sub > N <潜水艇class=“ a-plus-plus ”> 4 </sub> nanohybrids 极大地与太古的 g-C 相比被改进<潜水艇class=“ a-plus-plus ”> 3 </sub > N <潜水艇class=“ a-plus-plus ”> 4 </sub> nanosheets ，并且而且， nanohybrids 显示出驱散细菌的 biofilms 的提高的抗菌剂功效和能力。我们第一次证明 Ag/g-C < 潜水艇 class= “ a-plus-plus ” > 3 </sub > N < 潜水艇 class= “ a-plus-plus ” > 4 </sub> nanohybrids 是在可见的光下面的有效杀菌代理人照耀，和罐头也为 biofilm 提供一个新方法消除。Ag/g-C 的提高的抗菌剂性质和破坏 biofilm 能力 < 潜水艇 class= “ a-plus-plus ” > 3 </sub > N < 潜水艇 class= “ a-plus-plus ” > 4 </sub> nanohybrids 可以为许多提供生物医学的应用。

关 键 词：graphitic carbon nitride Ag/g-C3N4 nanohybrids antibacterial platform reactive oxygen species（ROS） BIOFILM 

分 类 号：TQ127.11[化学工程—无机化工] O614.122[理学—无机化学]