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作 者:雷国强[1]
机构地区:[1]广东医学院附属西乡人民医院,广东深圳518102
出 处:《今日药学》2015年第5期366-368,共3页Pharmacy Today
摘 要:目的探讨抗菌药物专项整治活动对本院普外科Ⅰ类切口手术在围术期抗菌药物预防性使用的影响。方法采用回顾性方法,对2011-01~10和2014-01~10本院普外科Ⅰ类手术围术期预防使用抗菌药物的使用率、药物品种选择、首次给药时机、用药疗程等方面进行统计和对比分析。结果预防用抗菌药物使用率由整治前的97.50%下降到整治后的29.50%,使用强度由82.64DDD下降至25.68 DDD,首次给药时机在术前0.5~2 h使用比例由45.64%提高至93.22%,用药疗程在24h以内的比例由12.82%提高至49.15%,药物品种选择、联合用药和更换品种的合理性等各项指标得到有效改善。结论抗菌药物专项整治活动降低了普外科Ⅰ类切口手术抗菌药物预防使用比例,提高了抗菌药物合理应用水平。OBJECTIVE To investigate antibiotic prophylaxis for type I incision operation of general surgical by antibiotics special rectification. METHODS By retrospective analysis, the prophylactic application ofantibiotics in type I incision surgery in 2011-01~ 10 and 2014-01~ 10 were analyzed statistically in respects of utilization ratio, drug selection, medication timing, and duration. RESULTS After rectification, the rate of antimicrobial prophylaxis use decreased from 97.50% to 29.05%, while antibiotics use density from 82.64 to 25.68 DDDs, timing and duration of prophylaxis increased from 45.64%, 12.82% to 93.22%, 49.15%, respectively ; the rate of reasonable selection, combination and replacement of antibiotics were improved significantly. CONCLUSION Antibiotics special rectification activities can reduce the rate of antibiotic prophylaxis application, and improve the rational antibiotic application.
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