胆碱能杀虫剂中毒后发生中间综合征的相关危险因素  

Related risk factors of intermediate syndrome after cholinergic pesticides poisoning

作　　者：任彩红[1] 王增民[1] 肖素红[1] 

机构地区：[1]漯河市中心医院(漯河医专一附院)急救中心,462000

出　　处：《中国实用医药》2015年第13期26-27,共2页China Practical Medicine

摘　　要：目的探讨胆碱能杀虫剂中毒后发生中间综合征(IMS)的相关危险因素。方法收集324例患者的一般临床资料包括年龄、性别、基础疾病,以及毒物类型、中毒途径、治疗方法、IMS的临床特征。观察IMS的发病率,并分析其相关危险因素。结果 16.4%患者发生IMS,死亡率39.6%,其中男性占66.7%,且年龄>45岁是IMS进展的显著危险因素[RR 2.67,95%CI(1.31,4.72),P<0.05],而多次洗胃则是保护因素[RR 0.35,95%CI(0.11,0.79),P<0.05]。结论 IMS的发生与年龄>45岁、洗胃次数多少相关,而与洗胃时机和毒物类型无关。Objective To investigate related risk factors of intermediate syndrome （IMS） after cholinergic pesticides poisoning.Methods Collections were made on clinical data of age, gender, underlying disease, poison type, poisoning route, treatment method, and clinical characteristics of IMS in 324 cases. Morbidity of IMS was observed to analyze its related risk factors.Results There were 16.4% of the patients had IMS with the mortality rate as 39.6%, and 66.7% of them was male patients. Aging 〉45 years old was a significant risk factor of IMS [（RR 2.67, 95%CI（1.31, 4.72）,P〈0.05）], while repeated gastric lavage is the protective factor [（RR 0.35, 95%CI（0.11, 0.79）,P〈0.05）].Conclusion There is a correlation in IMS, age 〉45 years old and gastric lavage times, while IMS is not related with time of gastric lavage and poison type.

关 键 词：中毒 中间综合征 危险因素 

分 类 号：R595.4[医药卫生—内科学]