双歧杆菌活菌制剂联合柳氮磺吡啶保留灌肠治疗溃疡性结肠炎的临床研究  

Clinical studiy of bifidobacterium viable preparation joint willow nitrogen sulfonyl pyridiue enema in the treatment of ulcerative colitis

作　　者：龚珍民 

机构地区：[1]江苏省邳州市人民医院消化科,江苏邳州221300

出　　处：《医药前沿》2015年第13期29-30,共2页Journal of Frontiers of Medicine

摘　　要：目的：探讨双歧杆菌活菌制剂联合柳氮磺吡啶保留灌肠治疗溃疡性结肠炎的临床效果。方法：将60例溃疡性结肠炎患者随机分为对照组和观察组，各30例，对照组给予柳氮磺吡啶保留灌肠治疗，观察组在对照组基础上联合双歧杆菌活菌制剂治疗，比较两组总有效率以及腹痛、便血、腹泻消失时间。结果：观察组总有效率为93.33%，对照组总有效率为70.00%，观察组疗效明显优于对照组（P＜0.05），且观察组腹痛、便血、腹泻消失时间明显短于对照组，两组比较差异具有统计学意义（P＜0.01）。结论：双歧杆菌活菌制剂联合柳氮磺吡啶保留灌肠治疗溃疡性结肠炎，可有效缓解患者临床症状，提高治疗效果，值得临床进一步研究推广。ObjectiveTo investigate the Bifidobacterium combined with sulfasalazine enema clinical effect in the treatment of ulcerative colitis.Methods 60 patients with ulcerative colitis were randomly divided into control group and observation group, 30 cases in each group. The control group given willow nitrogen sulfonyl pyridine enema treatment. Observation group in the control group on the basis of combined with bifidobacterium viable. Compare the two groups of the total effective and rate of diarrhea, and abdominal pain, hematochezia, the disappearance of the time.Results Observation group total effective rate was better than control group （P 〈 0.05）, the observation group of abdominal pain, hematochezia, time of the disappearance of diarrhea is obviously shorter than the control group, difference has statistical significance （P 〈 0.01）.Conclusions Bifidobacterium viable preparation joint willow nitrogen sulfonyl pyridine enema in the treatment of ulcerative colitis, which can effectively relieve patients＇ clinical symptoms, can improve the treatment effect, is worth popularizing further clinical research.

关 键 词：双歧杆菌活菌制剂 柳氮磺吡啶 保留灌肠 溃疡性结肠炎 

分 类 号：R453[医药卫生—治疗学]