脉冲动态核极化增强的NMR和MRI系统研究（英文）  

Development of Pulsed Dynamic Nuclear Polarization for Enhancing NMR and MRI

作　　者：贺玉贵[1,2] 冯继文[1] 张志[1,3] 王超[1,3] 倪胜[1] 胡少斌[1] 王东[1] 陈方[1] 刘买利[1] 刘朝阳[1] 

机构地区：[1]波谱与原子分子物理国家重点实验室,武汉磁共振中心(中国科学院武汉物理与数学研究所),武汉430071 [2]武汉光电国家实验室(筹),华中科技大学光学与电子信息学院,武汉430074 [3]中国科学院大学,北京100049

出　　处：《波谱学杂志》2015年第2期393-398,共6页Chinese Journal of Magnetic Resonance

基　　金：Grant from the special equipment of scientific instrument of Chinese Academy of Sciences,the Ministry of Science and Technology of China(2011YQ120035);the National Natural Science Foundation of China(11405264)

摘　　要：该文介绍了一种自行设计和构建的可扩展脉冲动态核极化谱仪,可以实现核磁共振波谱与磁共振成像的功能.该仪器的新颖设计主要有:1)采用基于PCIe的分布式总线结构,能够极大地提高数据传输效率和通信可靠性,实现精确控制脉冲序列;2)采用外部高速的DDR芯片存储脉冲序列元素和FID数据,可以极大的提高脉冲序列的执行速度,减少快速成像序列的TR时间间隔;3)采用时钟移相技术,可以精确产生分辨率为纳秒级别的数字脉冲.最后对该仪器的动态核极化-磁共振波谱与核磁共振成像功能进行了实验验证.In this report, we present a pulsed dynamic nuclear polarization （DNP） system, being reconfigurable for DNP enhanced magnetic resonance imaging （DNP-MRI） and magnetic resonance spectroscopy （DNP-MRS）. Several novel console designs are proposed in the presented DNP system. A distributed digital architecture based on Peripheral Component Interconnect Express （PCIe） has been developed, so as to significantly improve the efficiency of data transmission and communication reliability as well as the precise control of pulse sequence. An external high speed Double Data Rate （DDR） memory chip is used for storing FID data and pulse sequence elements, greatly speeding up the execution of the pulse sequence and reducing the interval of TR and improving the accuracy of TR in image sequence. Using clock phase-shift technology, we can produce digital pulse accurately with high timing resolution of nanosecond timescales. Finally, two experimental examples for DNP-MRS and DNP-MRI are shown.

关 键 词：核磁共振(NMR) 磁共振成像(MRI) 脉冲动态核极化 控制台 

分 类 号：O482.53[理学—固体物理]