肿瘤治疗新策略:联合药物疗法同时杀伤肿瘤细胞和肿瘤干细胞  

A new cancer treatment strategy: combined drug therapy to simultaneously kill tumor cells and cancer stem cells

作　　者：王美平[1] 巩志荣[1] 张翮[1] 钟延强[1] 鲁莹[1] 

机构地区：[1]上海市第二军医大学药学院药剂学教研室,上海200433

出　　处：《中国新药杂志》2015年第10期1128-1133,1144,共7页Chinese Journal of New Drugs

摘　　要：近年来,同时杀伤肿瘤细胞和肿瘤干细胞的联合药物疗法在肿瘤治疗中表现出了良好的应用前景。本文对目前已报道联合药物疗法中的药物品种、给药系统、肿瘤和肿瘤干细胞类别、肿瘤的治疗和预防效果进行综述,对联合药物疗法目前面临的问题进行分析阐述,为其进一步研究开发和临床应用提供新思路。In recent years, the combined drug therapy for simultaneously killing tumor cells and cancer stem cells has shown a great prospect in cancer treatment. In this article, we reviewed drug varieties and delivery systems, tumors and cancer stem cells classes, anticancer treatment and preventive effects, and analyzed the prob- lems currently faced on combined drug therapy.

关 键 词：肿瘤细胞 肿瘤干细胞 联合药物疗法 肿瘤治疗 

分 类 号：R979.1[医药卫生—药品]