复发性流产主动免疫治疗干预（附31例分析）  

Analysis of 31 cases on lymphocyte active immunization for treatment of recurrent spontaneous abortion

作　　者：李弘[1] 惠董娜[1] 任文娟[1] 王怀秀[1] 宋玉梅[1] 

机构地区：[1]山西省人民医院生殖医学科,太原030012

出　　处：《中国实用医刊》2015年第13期69-70,共2页Chinese Journal of Practical Medicine

摘　　要：目的探讨异体淋巴细胞主动免疫治疗对复发性流产的干预疗效。方法选择2012年5月至2013年8月原因不明复发性流产患者50例，其中干预组31例准备怀孕前先给予淋巴细胞主动免疫治疗2个月，怀孕后应用黄体支持；对照组19例单纯给予孕后黄体支持治疗。结果干预组治疗成功率为85．2％，对照组为20％，差异有统计学意义（P〈0．01）。结论采用异体淋巴细胞主动免疫治疗对复发性流产患者进行干预，临床效果满意。Objective To investigate the clinical effect of active immunization with lymphocytes on recurrent spontaneous abortion. Methods Fifty patients with unexplained recurrent spontaneous abortion （URA） were randomly divided into two groups. Thirty one cases in the treatment group were treated by pre- pregnancy lymphocyte immunotherapy and conventional luteal support post-pregnancy, and nineteen cases in the control group were treated with conventional luteal support post-pregnancy merely. The incidences of pregnancy and spontaneous abortion were observed. Results The rate of pregnancy was 85.2% in the treatment group and 20% in the control group, there was significant difference between the two groups（P 〈 0. 01 ）. Conclusions Lymphocyte active immunization for URA is safe and has satisfactory effect.

关 键 词：复发性流产 淋巴细胞 主动免疫 封闭抗体 

分 类 号：R714.21[医药卫生—妇产科学]