妊娠期高血压疾病并发胎盘早剥与母婴不良预后的关系  

Relationship between Hypertensive Disorder Complicating Pregnancy Combined with Maternal Placental Abruption and Poor Prognosis of Maternal and Infant

作　　者：龙娅静 张卫萍[1] 

机构地区：[1]重庆市巴南区人民医院产科,重庆401320

出　　处：《医学综述》2015年第11期2069-2070,共2页Medical Recapitulate

摘　　要：目的探讨妊娠期高血压疾病(HDCP)合并胎盘早剥与母婴不良妊娠结局的关系。方法选取2008年5月至2012年12月重庆市巴南区人民医院产科收治的47例HDCP并发胎盘早剥患者(观察组)和47例正常妊娠孕妇(对照组),对比两组妊娠时间、围生期并发症、新生儿体质量、新生儿窒息、呼吸困难以及围生儿病死率。结果观察组孕妇妊娠时间显著短于对照组[(35.2±1.8)周比(39.3±1.6)周,P<0.01],同时胎盘子宫卒中、产后弥散性血管内凝血及产后大出血等围生期并发症发生率均显著高于对照组(19.1%比2.1%,21.3%比4.3%,17.0%比2.1%,P<0.05或P<0.01);观察组新生儿出生体质量显著低于对照组[(2.11±0.52)kg比(3.67±0.54)kg,P<0.01],新生儿窒息、新生儿呼吸困难发生率以及围生儿病死率均显著高于对照组(21.3%比2.1%,19.1%比2.1%,4.5%比0.0%,P<0.05或P<0.01)。结论 HDCP并发胎盘早剥严重影响母婴安全与健康,而关于该病最为有效的治疗措施即为终止妊娠。但仍应根据具体情况进行综合考虑,以充分保证母婴安全。Objective To discuss the relationship between hypertensive disorder complicating pregnancy （HDCP） combined with maternal placental abruption and poor prognosis of maternal and infant.Methods A total of 47 patients with HDCP combined with maternal placental abruption admitted in Department of Obstetrics,People′s Hospital of Banan District from May 2008 to Dec.2012 were selected as the observation group,and another 47 normal pregnant women were selected as the control group.The gestation time,perina-tal complications,birth weight,incidences of neonatal asphyxia and neonatal dyspnea,and perinatal mortality were compared between the two groups.Results The gestation time of the observation group was significant-ly shorter than that of the control group[（35.2 ±1.8） weeks vs （39.3 ±1.6） weeks,P 〈0.01],inci-dences of perinatal complications such as placenta uterine stroke ,postpartum disseminated intravascular coag-ulation（DIC）,and postpartum hemorrhage of the observation group were significantly higher than those of the control group（19.1% vs 2.1%,21.3% vs 4.3%,17.0% vs 2.1%,P〈0.05 or P〈0.01）;neonatal birth weight of the observation group was significantly lower than the control group [（2.11 ±0.52） kg vs （3.67 ±0.54） kg,P〈0.01];incidences of neonatal asphyxia and neonatal respiratory difficulty,and peri-natal child mortality rate of the observation group were significantly higher than those of the control group （21.3% vs 2.1%,19.1% vs 2.1%,4.5% vs 0.0%,P〈0.05 or P〈0.01）.Conclusion HDCP com-bined with placental abruption has serious impact on the health and safety of maternal and infant , the most effective treatment for the disease is termination of pregnancy.But it is still necessary to synthetically consider according to the specific situation in order to fully ensure the safety of maternal and infant .

关 键 词：妊娠期高血压疾病 胎盘早剥 母婴预后 

分 类 号：R714.2[医药卫生—妇产科学]