乙型肝炎病毒e抗体在HBV感染中的作用  

The Function of Anti-HBe in Patients with HBV infection

作　　者：王金侠[1] 石华[2] 

机构地区：[1]秦皇岛市第二医院,河北秦皇岛066600 [2]秦皇岛市第一医院,河北秦皇岛066000

出　　处：《标记免疫分析与临床》2015年第6期590-592,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：长期以来,病毒载量和谷丙转氨酶水平是判断抗-HBe阳性慢性乙型肝炎是否需要治疗的关键指标,而忽略了抗-HBe本身在疾病进展中的作用。目前,随着对抗-HBe研究的不断增多,逐渐对抗-HBe在HBV感染中的作用产生了新的认识,本文对发生血清学转换后HBV-DNA病毒载量的变化、抗-HBe与肝组织病变的关系等方面进行综述。Viral load and alanine aminotransferase （ALT）levels have been the key points for making a decision in the treatment of anti- HBe positive chronic hepatitis B for a long time, and ignoring the role of anti- HBe itself in the progress of the disease. Nowadays knowledge of the function of anti-HBe in HBV infection is increasing, along with the in-depth studies of anti-HBe. This study is to summarize the changes of HBV-DNA viral load after seroconversion and the correlation between anti-HBe and the histological evaluation of liver.

关 键 词：抗-HBE HBV HBEAG 血清学转换 

分 类 号：R512.62[医药卫生—内科学]