热毒宁注射液联合α-干扰素治疗病毒性毛细支气管炎患儿疗效及安全性分析  

Clinical effects and security of interferon α combined with reduning injection in treating viral bronchiolitis patients

作　　者：崔楠[1] 

机构地区：[1]北京仁和医院儿科,北京102600

出　　处：《医药论坛杂志》2015年第5期65-66,共2页Journal of Medical Forum

摘　　要：目的探讨在病毒性毛细支气管炎患儿治疗中应用热毒宁注射液与α-干扰素联合疗法的临床效果及安全性。方法选取北京仁和医院2012年3月至2014年3月收治的病毒性毛细支气管炎患儿160例为研究对象,随机分为研究组和对照组,每组各80例,对照组行常规治疗方法;观察组在对照组治疗基础上,加用热毒宁与α-干扰素,比较两组治疗效果。结果观察组治疗总有效率为93.75%,同对照组的82.50%比较,明显较高,差异具有统计学意义(P<0.05),观察组症状及体征缓解时间同对照组比较,明显较短,差异具有统计学意义(P<0.05),两组患儿不良反应发生率无明显差异(P>0.05)。结论在对病毒性毛细支气管炎进行治疗时,使用α-干扰素联合热毒宁注射液辅助治疗,可明显提高治疗效果,缩短治疗时间,促进患儿恢复,且具有较高安全性,值得推广。Objective To investigate the clinical efficacy and security of interferon α combined with reduning injection in treating viral bronchiolitis. Methods Selected 160 children with viral bronchiolitis from March 2012 to March 2014 and randomly divided them into observation group and control group, each with 80 cases. The control group was given conventional treatment and the observation group was given reduning with interferon α on the basis of control group. Observed these two groups＇ treatment efficacy. Results The efficiency in observation group was obviously higher than that of the control group, its symptom and shorter than the control group （P 〈 0. 05 ）. There was no obvious difference in these two groups＇ incidence of adverse reactions. Conclusion In treating viral bronchiolitis, interferon α combined with reduning can obviously improve clinical efficacy, shorter treatment time, which should be widely applied in clinical.

关 键 词：毛细支气管炎 干扰素 热毒宁 临床观察 

分 类 号：R725.6[医药卫生—儿科]