热休克蛋白70及其在运动中作用研究进展  

Research Progress of HSP70 and Its Effects in Exercises

作　　者：郑妩媚 王福文[1,2] 

机构地区：[1]山东省医学科学院药物研究所,山东济南250062 [2]济南大学山东省医学科学院医学与生命科学学院,山东济南250062

出　　处：《食品与药品》2015年第3期223-227,共5页Food and Drug

基　　金：山东省自然科学基金项目资助(ZR2009CM089)

摘　　要：热休克蛋白70(heat shock protein 70,HSP70)是一种在应激条件下诱导高表达的伴侣蛋白,与运动关系密切,在机体运动过程中起重要作用。近年,HSP70已成为较受重视的心肌内源性保护途径之一。本文主要介绍了HSP70的生物学特性及其对运动性心肌损伤保护作用的研究进展,以冀为合理进行运动训练提供依据。Heat shock protein 70 （HSP70） is a molecular chaperone that is highly expressed in response to stress and closely related to exercises. HSP70 plays an important role in body movement, and is considered as a new endogenous protection approach for myocardium in recent years. The research progress in biological characteristics of HSP70 and its protective effect on myocardial damage induced by exercises is reviewed in this paper, to provide basis for reasonable training in exercises.

关 键 词：热休克蛋白70 运动 研究进展 

分 类 号：Q51[生物学—生物化学] G804.2[文化科学—运动人体科学]