深圳市2005—2013年脊髓灰质炎疫苗相关病例流行病学分析  

Epidemiological Analysis on the Vaccine-associated Paralytic Poliomyelitis in Shenzhen from 2005 to 2013

作　　者：杨洁[1] 黄芳[2] 张世英[2] 林喜乐[1] 杨卫红[2] 卢紫燕[2] 

机构地区：[1]深圳市罗湖区疾病预防控制中心,广东深圳518020 [2]深圳市疾病预防控制中心

出　　处：《中国初级卫生保健》2015年第6期64-65,共2页Chinese Primary Health Care

基　　金：深圳市科技研发资金项目(JCYJ 20130401153529389)

摘　　要：目的了解深圳市脊灰疫苗相关病例(vaccine-associated paralytic poliomyelitis,简称VAPP)发生情况及流行病学特征。方法采用流行病学方法对深圳市2005—2013年VAPP病例进行分析,VAPP发生率=某阶段VAPP发生数/同期OPV接种量(剂)。结果 2005—2013年VAPP病例总发生率为1.90/100万,服苗者VAPP发生率为1.90/100万,无接触者VAPP发生;其中首次服苗VAPP发生率为4.23/100万;所有病例均为6个月以下幼儿;发生在7月份的病例较多;地区分布以宝安区病例相对较集中。结论阻断脊灰野病毒传播后,还需要停止使用脊髓灰质炎减毒活疫苗(简称OPV),以最终实现消灭脊灰的目标。OBJECTIVE To find out the occurrence and the epidemiological character of the vaccine-associated paralytic poliomyelitis in Shenzhen from 2005 to 2013. METHODS Epidemiological study method. The VAPP incidence = the cases of VAPP/the number of OPV immunization in the same period. RESULTS The total incidence of the VAPP was 1.90/1 000 000 and that of the vaccinated cases were 1.90/1 000 000. There was none contact cases reported. The incidence of the vaccinated cases after the fist close of OPV vac- cine was 4.23/1 000 000. And all cases were childre below 6 months old. Gathering tendency in distribution of place and time was found, most cases occurred in July and and distributed in Baoan District. CONCLUSION In order to realize the goal of polio-free, it should stop to use oral polio vaccine（OPV） after the spread of the wild polio virus was terminated.

关 键 词：脊髓灰质炎 急性弛缓性麻痹 疫苗相关病例 

分 类 号：R186[医药卫生—流行病学]