合理使用抗生素对减少儿童反复呼吸道感染的研究  

THE STUDY OF RATIONAL ADMINISTRATION OF ANTIBIOTICS TO REDUCE THE INCIDENCE OF RECURRENT RESPIRATORY TRACT INFECTION IN CHILDREN

作　　者：侯俏珍[1] 何丽雅[1] 邓力[1] 黄俪峰[1] 何婉儿[1] 江文辉[1] 吴佩琼[1] 

机构地区：[1]广州市妇女儿童医疗中心,广东广州510000

出　　处：《现代医院》2015年第6期86-88,91,共4页Modern Hospitals

基　　金：广东省医学科研基金(编号:WSTJJ2012121536010219-701223582X)

摘　　要：目的为了给防治儿童反复呼吸道感染(RRTIs)提供依据,笔者研究广东珠三角地区学龄前儿童RRTIs与合理使用抗生素的内在关系,重点研究医源性因素。方法研究抗生素专项整治前后12个月,2 227例反复呼吸道感染儿童患上呼吸道感染、支气管炎、肺炎的发病率。结果在抗生素调控之后3岁以下婴幼儿上呼吸道感染和支气管炎的发病率减少有显著性差异;3岁以下婴幼儿肺炎的发病率改变无显著性差异;3岁以上儿童患上呼吸道感染、支气管炎、肺炎的发病率改变均无显著性差异。结论小于3岁的婴幼儿多以病毒感染为主,不合理使用抗生素有副作用,规范合理使用抗生素以来,抗生素产生的毒副作用减少了,小于3岁的婴幼儿患上呼吸道感染和支气管炎的发病率也有所减少。Objective To provide the scientific evidence for the prevention and treatment of RRTIs, the re- lated factors RRTIs in infants of Guangdong and rational administration were analyzed. This study was aimed to inves- tigate the iatrogenic factor in children＇s RRTIs. Methods Anterior- posterior 12 months special -purpose set in or- der antibiotic, and the incidence of Upper respiratory tract infection and Bronchitis and Pneumonie in 2 227 cases with RRTIs were compared and analyzed. Results After special - purpose set in order antibiotics, significant differ- ence was noted in incidence rate of Upper respiratory tract infection and Bronchitis in RRTIS 〈 3 years old. No sig- nificant difference was noted in incidence rate of Pneumonic in RRTIS 〈 3 years old. No significant difference was noted in incidence rate of Upper respiratory tract infection and Bronchitis and Pneumonie in RRTIs 〉 3 years old. Conclusion Infants 〈 3 years old are susceptible to viral infection, and irrational use of antibiotics have side effects. After special - purpose set in order antibiotics, antibiotics toxicity reduces. Incidence rate of Upper respirato- ry tract infection and Bronchitis decrease in infants 〈 3 years old.

关 键 词：反复呼吸道感染 抗生素 耐药菌 

分 类 号：R725.6[医药卫生—儿科]