晚期妊娠合并潜伏期梅毒对母婴的影响及防治对策  

Impact of latent syphilis with late pregnancy on the maternal and infant and prevention countermeasures

作　　者：黄密芬 顾海娜 

机构地区：[1]岱山县第二人民医院妇产科,浙江舟山316281 [2]舟山市妇幼保健院妇产科,浙江舟山316000

出　　处：《中国性科学》2015年第6期90-93,共4页Chinese Journal of Human Sexuality

摘　　要：目的:探究与分析晚期妊娠合并潜伏期梅毒对母婴的影响及防治对策。方法:选取我院自2010年10月至2014年10月收治的晚期妊娠合并梅毒患者30例作为观察组,另选择同时期入院的30例晚期妊娠孕妇作为对照组,对比两组孕妇的妊娠结局、新生儿预后情况及孕妇血RPR滴度与先天性梅毒儿并发症的关系。结果:观察组与对照组孕妇妊娠结局为足月产、早产、死胎死产及产褥感染相比组间均具有明显差异(χ2=4.34,P<0.05;χ2=4.19,P<0.05;χ2=3.91,P<0.05;χ2=3.96,P<0.05)。观察组与对照组新生儿预后为正常新生儿、窒息儿、低体重儿、先天性梅毒儿、潜伏期梅毒儿及新生儿死亡相比组间均具有明显差异(χ2=9.67,P<0.05;χ2=5.25,P<0.05;χ2=5.11,P<0.05;χ2=5.28,P<0.05;χ2=4.56,P<0.05;χ2=4.56,P<0.05)。观察组孕妇血RPR>1∶8与观察组孕妇血RPR<1∶8发生肝功能异常与骨损害相比组间有明显差异(χ2=5.66,P<0.05;χ2=5.47,P<0.05)。结论:晚期妊娠合并潜伏期梅毒可对母婴健康造成影响,对梅毒行早期诊断与治疗至关重要,可降低先天性梅毒儿的发病率。Objectives： To explore and analyze the impact of latent syphilis with late pregnancy on maternal and infant and prevention countermeasures. Methods： 30 cases of late pregnancy patients with syphilis in our hospital from October 2012 to October 2012 were selected as observation group. 30 late pregnancy patients hospitalized in our hospital in same period were selected as control group. The pregnancy outcome and neonatal prognosis and rela- tions between the degree of pregnant women blood RPR drops and congenital syphilis and complications of the two groups were compared. Results： The full term pregnancy outcome, premature birth, stillbirth and puerperal infection between observation group and control group were of significant differences （X2 = 4.34, P 〈 0. 05; X2 = 4. 19, P〈0.05; X2 =3.91,P〈0.05; X2 =3.96, P〈0.05）. The normal newborn, suffocation, low birth weight, congenital syphilis, latent syphilis and neonatal death outcomes of observation group and control group were of significant differences （X2=9.67, P〈0.05; X2=5.25, P〈0.05; X2 =5-11, P〈0.05; X2 =5.28, P〈0.05; X2= 4.56, P 〈0. 05 ; x2 =4.56, P 〈0. 05）. The abnormal liver function and the bone damage of Blood RPR 〉 1：8 of observation group and blood RPR 〈 1：8 of observation group were of significant （ X2 =5.66, P 〈0. 05 ; x2 =5.47, P 〈 0. 05）. Conclusion： Late pregnancy with latent syphilis can affect the outcomes of maternal and infant health. It is important for early diagnosis and treatment of syphilis, thereby reducing the incidence of congenital syphilis children.

关 键 词：晚期妊娠 潜伏期梅毒 妊娠结局 先天性梅毒 

分 类 号：R759.12[医药卫生—皮肤病学与性病学]