重症监护病房与普通病房铜绿假单胞菌耐药性比较分析  

Comparative analysis of drug resistance of Pseudomonas aeruginosa in ICU and general ward

作　　者：姚兴伟[1] 郭楠[1] 金艳红[2] 林英[1] 杨琦[1] 马婧涵 李慧萍[1] 

机构地区：[1]北京中医药大学第一临床医学院,北京100700 [2]黑龙江中医药大学附属第二医院

出　　处：《中国实验诊断学》2015年第6期949-950,共2页Chinese Journal of Laboratory Diagnosis

摘　　要：目的比较我院重症监护病房(ICU)与普通病房铜绿假单胞菌的耐药情况。方法收集我院2012年1月至12月间临床送检标本中分离出的铜绿假单胞菌385株,其中ICU 50株,普通病房335株。使用美国BD公司的PHOENIX-100微生物鉴定系统进行菌种鉴定和药物敏感性试验。用WHONET5.6软件进行数据统计分析。结果从本院临床标本中分离的铜绿假单胞菌主要来自于痰液标本。ICU病房送检标本中分离出的铜绿假单胞菌对临床常用的10种抗生素的敏感性均低于非ICU病房。结论铜绿假单胞菌是重症监护病房常见的致病菌,且多数对临床常用抗生素敏感性较差。加强临床抗生素的管理,合理使用抗生素能减少和延缓耐药菌株的出现。Objective To compare the drug resistance of Pseudomonas aeruginosa in ICU and general ward.Methods Strains were collected from January 2012 to December daily specimens,and there are 385 strains of pseudomonas aeruginosa isolated,ICU of 50 strains,335strains general ward.The identification and antibiotics susceptibility test（AST）were identified with BD PHOENIX-100.The antimicrobial resistance rates were analyzed by WHONET5.6software.Results Separation in clinical specimens of pseudomonas aeruginosa mainly from sputum specimens.ICU pseudomonas aeruginosa isolated in samples of 10 kinds of antibiotics commonly used for clinical susceptibility is lower than the Non-ICU.Conclusion Pseudomonas aeruginosa is the ICU common pathogenic bacteria,and most of the poor susceptibility to clinical commonly used antibiotics.To strengthen the management of clinical antibiotics,reasonable use of antibiotics can reduce and delay the emergence of resistant strains.

关 键 词：铜绿假单胞菌 耐药性 ICU 

分 类 号：R446.5[医药卫生—诊断学]