miRNA与糖尿病及其并发症综述  

Summary of mi RNA and its Conplions

作　　者：诸进晋 毛水龙[2] 

机构地区：[1]浙江中医药大学第二临床医学院 [2]浙江中医药大学基础医学院

出　　处：《黑龙江医药》2015年第3期460-464,共5页Heilongjiang Medicine journal

基　　金：浙江省大学生科技创新项目(2013R410042)

摘　　要：mi RNA(mi RNAs)是一类小(19-25核苷酸)、非编码RNA,它可作为内源性调节因子在转录后水平抑制靶m RNA表达。mi RNA能调控胰岛β细胞胰岛素的合成和分泌,与糖尿病及其并发症的发生发展相关,是目前糖尿病及其并发症研究中的热点。mi RNA（mi RNAs）is a small（containing about 19-25 nucleotides）, noncoding RNA, which serves as an endogenous factor to inhibit expression of mi RNA＇targets m RNA in post-transcriptional. Meanwhile, it is found that mi RNA play a key role in regulating islet beta cells＇ function of insulin synthesis and secretion, which is as well highly related to the development of diabetes and its complications,that is currently focused in studies on diabetes and its complications.

关 键 词：MIRNA 糖尿病 糖尿病并发症 

分 类 号：R587.1[医药卫生—内分泌]