甘油作为相转移催化剂催化合成喹喔啉类化合物  

Synthesis of quinoxaline derivatives using glycerol as phase transfer catalyst

作　　者：周文俊[1,2] 周丹[1] 张霞忠[1,2] 雷光东[1,2] 

机构地区：[1]内江师范学院化学化工学院,四川内江641112 [2]四川省高等学校"果类废弃物资源化重点实验室",四川内江641112

出　　处：《化学研究与应用》2015年第6期919-922,共4页Chemical Research and Application

基　　金：四川省教育厅研究基金项目(12ZB074;13ZB0002)资助

摘　　要：本文以绿色介质水为溶剂,甘油作为相转移催化剂,通过1,2-二羰基化合物和1,2-二胺类化合物缩合合成一系列喹喔啉类化合物。甘油作为生物柴油工业的主要副产品,无毒无害,可生物降解,有机合成中的应用为其找到了很好的应用前景。An efficient method had been developed for the synthesis of quinoxaline derivatives in water by the condensation of 1,2-dicarbonyl compounds with 1,2-diamines.Glycerol was found to be a sustainable phase transfer catalyst for the condensation,and excellent yields were obtained under this mild reaction condition.Glycerol（1,2,3-propanetriol or glycerin） was easily available as the main by-product of the biodiesel industry,had attracted attention as it is a versatile,cheap,and renewable feedstock and had been proven to be an environmentally friendly reaction media for the synthetic organic chemistry.

关 键 词：喹喔啉类化合物 1 2-二胺类化合物 1 2-二羰基化合物 水 甘油 

分 类 号：O626[理学—有机化学]