有机硒铬对高脂饮食加链脲佐菌素诱导的糖尿病小鼠的降血糖作用  

Organic Selenium Chromium to High Fat Diet Plus Chain with Urea,Diabetic Mice Induced by Bacteria Fall Blood Sugar Role

作　　者：冯润荷[1] 张淑坤[2] 盛晓英[2] 王鹏华[3] 

机构地区：[1]天津医学高等专科学校,天津市300222 [2]天津市南开医院 [3]天津医科大学代谢病医院

出　　处：《医学理论与实践》2015年第10期1261-1262,1273,共3页The Journal of Medical Theory and Practice

摘　　要：目的:探讨有机硒铬对高脂饮食加链脲佐菌素(Streptozotocin,STZ)诱导的糖尿病小鼠模型体重、血糖、甘油三酯(TG)和总胆固醇(TC)的影响。方法:36只雄性昆明小鼠,随机分为3组:对照(Control)组、高脂饮食糖尿病(High fat diet in diabetes,HFD+STZ)组、高脂饮食糖尿病+有机硒铬全蛋粉(Organic selenium chromium whole egg powder,OSCWEP)(HFD+STZ+OSCWEP)组。3周后测小鼠体重、血糖。4周时测定血清TG和TC。结果:OSCWEP能降低HFD+STZ诱导的糖尿病小鼠的体重、血糖和TG水平。结论:有机硒铬有明显降低糖尿病小鼠血糖和血脂的作用。Objective：The purpose of the research is to explore the influence of the organic selenium chromium on weight,blood sugar,triglyceride model（TG）and total cholesterol（TC）of diabetic mice induced by high-fat diets and streptozotocin（STZ）.Methods：36male kunming mice are divided into 3groups at random：control group,high fat diet in diabetes（HFD＋STZ）,high fat diet diabetes＋organic selenium chromium whole egg powder（OSCWEP）（HFD＋STZ＋OSCWEP）.Three weeks later,weight and blood sugar of the mice are tested.Four weeks later,the serum TG and TC are tested.Results：The weight,blood sugar and TG of the mice induced by HFD＋STZ can be reduced by OSCWEP.Conclusion：Organic selenium chromium has a remarkable effect on lowering the blood sugar and TG of the diabetic mice.

关 键 词：有机硒铬化合物 实验性糖尿病模型 高脂血症 

分 类 号：R587.1[医药卫生—内分泌]