小儿脓毒血症死亡的相关危险因素分析  

To Analyse the Risk Factors of Death in Children with Sepsis

作　　者：谢云惠[1] 沈晓翠 

机构地区：[1]云南省第二人民医院儿科,云南省昆明市650021

出　　处：《医学理论与实践》2015年第12期1559-1560,共2页The Journal of Medical Theory and Practice

摘　　要：目的:分析小儿脓毒血症死亡的相关危险因素,以期降低患儿死亡率。方法:回顾性分析310例小儿脓毒血症患者的临床资料,分析小儿脓毒血症死亡的危险因素,采用SPSS19.0软件进行分析。结果:78例患儿死亡,死亡率为25.16%,单因素分析显示,C-反应蛋白、降钙素原、小儿危重症评分、有无器官衰竭、谷草转氨酶、谷丙转氨酶、血肌酐、pH值、血乳酸、血小板是脓毒血症患儿死亡的危险因素,非条件Logistic多因素回归分析结果显示,降钙素原、小儿危重症评分、有无器官衰竭、血小板是引起患儿死亡的独立危险因素(P均<0.01)。结论:引起脓毒血症患儿死亡的危险因素较多,降钙素原、小儿危重症评分、有无器官衰竭、血小板是引起患儿死亡的独立危险因素。Objective： To analyse the risk factors of death in children with sepsis, in order to reduce the mortality rate of children with sepsis. Methods.. This was a prospective study, 310 cases of pediatric patients with sepsis was stud- ied. The death risk of factors in children with sepsis was analysis by SPSS19.0 software. Results： 78 cases died, the mor- tality was 25.16%. Univariate analysis showed that, the risk factors of death in children with sepsis were C-reactive protein, procalcitonin, pediatric critical illness score, organ failure or not, aspartate aminotransferase, alanine amin- otransferase, serum creatinine, pH, lactate and platelet. Unconditioned logistic regression analysis showed that procalci- tonin, pediatric critical illness score , organ failure or not, platelet were the independent risk factors causing death in children with sepsis （all P〈0. 01）. Conclusion：There were many risk factors of death in children with sepsis,procalci- tonin, pediatric critical illness score, organ failure or not, platelet were the independent risk factors causing death in children with sepsis.

关 键 词：脓毒血症 死亡 危险因素 

分 类 号：R725[医药卫生—儿科]