联合血浆置换治疗急性重症有机磷农药中毒31例临床分析  

The Clinical Analysis of 31 Patients with Acute Severe Organophosphorus Pesticide Poisoning Combined Treatment with Plasma Exchange

作　　者：严仲文[1] 叶惠芬[1] 蒋友明[2] 曾少平 周碧容[4] 邹文涛[1] 

机构地区：[1]广东省东莞市中心血站,523000 [2]广东省东莞市厚街医院 [3]广东省东莞市三局医院 [4]深圳市坪山新区人民医院

出　　处：《岭南急诊医学杂志》2015年第2期130-131,134,共3页Lingnan Journal of Emergency Medicine

摘　　要：目的:探讨血浆置换(PE)治疗急性重症有机磷农药中毒(ASOPP)的疗效。方法:将2011年1月-2014年5月收治的ASOPP患者62例随机分为对照组和研究组各31例,分别常规疗法和联合应用PE治疗,比较两组的临床疗效。结果:与对照组相比,研究组阿托品化、显著效果的时间和住院时间均明显缩短,中间综合征、反跳例数、死亡率均明显减少,治愈率明显增高,P均<0.05。结论:在常规治疗的基础上联合PE治疗ASOPP的抢救成功率高,死亡率低,并发症少。Objective： To explore the effect of patients with acute severe organophosphorus pesticide poisoning （ASOPP） combined treatment with plasma exchange（PE）. Methods： 62 patients with ASOPP from Jan 2011 to May 2014 were randomly divided into control group （n=31） and research group（n=31 ） treated by conventional therapy and combined PE based on the conventional therapy respectively. The clinical effects were compared between the two groups. Results： Compared with control group, atropinization time and hospitalization time were significantly shorter, intermediate syndrome, atropine rebound and mortality were significantly less, the cure rate was significantly higher in the research group, all P〈0.05. Conclusion： There is a high successful rescue rate, few mortality and complications for patients with ASOPP treated by PE combined with conventional therapy.

关 键 词：血浆置换 急性有机磷农药中毒 重症 临床疗效 

分 类 号：R595.4[医药卫生—内科学]