应用快速加温透析配液设备对超敏C反应蛋白的影响  

The influence of application of fast heating-up dialysate dispensing equipment on high sensitivity C reactive protein

作　　者：苏东东[1] 郭赤[2] 周露[1] 车华[1] 赵育新[1] 

机构地区：[1]广州军区武汉总医院血透中心,湖北武汉430070 [2]广州军区武汉总医院医学工程科,湖北武汉430070

出　　处：《中国医学装备》2015年第6期37-39,共3页China Medical Equipment

摘　　要：目的:探讨快速加温透析配液对维持性血液透析(MHD)患者超敏C反应蛋白(hs-CRP)的影响。方法:选取长期MHD患者34例,对其进行MHD自身对照观察,并将其分为两组,在2010年冬季使用传统配液法为MHD2010组;2011年冬季使用快速加温透析配液法为MHD2011组。同时抽取30名健康体检者为对照组。对三个组随访3个月,分别比较三组在0月、3个月测定的血清hs-CRP水平。结果:1与对照组相比,MHD2010组及MHD2011组的hs-CRP水平明显升高,差异有统计学意义(t=3.345,P<0.05);2随访3个月后MHD2011组和MHD2010组hs-CRP水平与自身治疗前比较都有所下降,差异有统计学意义(分别t=3.346,t=3.356,P<0.05);3治疗后,MHD2011组和MHD2010组hs-CRP水平相比较,差别无统计学意义(t=1.019,P>0.05)。结论:MHD患者存在微炎症状态,与传统配液法相比,快速加温透析配液法也可降低hs-CRP水平。Objective： To investigate the influence of fast heating-up dialysate dispensing equipment on high sensitivity C reactive protein of maintenance hemodialysis. Methods： We firstly got thirty health people population（12 males and 18 females, mean age 46.18±16.35）, thirty-four patients with maintenance hemodialysis（20 males and 14 females, mean age 50.35±14.48）. While MHD thirty-four patients were conducted by self-controlled trial, respectively in the winter of 2010 using conventional method （MHD2010 group）, 2011 for fast heating-up dialysate dispensing equipment method （MHD2011 group）, followed up for 5 months, compared serum hs-CRP levels of three groups of 0 month, third month. Results： （1）Compared with the healthy group, hs-CRP levels of MHD2010 group and MHD2011 group were significantly increased, the difference was statistically significant（t=3.545, P〈0.05）. （2）Followed-up for three months, hs-CRP levels of MHD2011 group and MHD2010 group were declined, the difference was statistically significant（t=5.546, P〈0.05）. （5）After treatment, the hs-CRP levels of MHD2011 group and MHD2010 group compared, The difference was not statistically significant （t= 1.019, P〉 0.05）. Conclusion： Micro-inflammatory state, exists in patients with maintenance hemodialysis, fast heating-up dialysate dispensing equipment could reduce the levels of hs-CRP, the same to conventional method.

关 键 词：血液透析 透析液 配液设备 超敏C反应蛋白 

分 类 号：R197.39[医药卫生—卫生事业管理]