自制紫草浸膏外用治疗大鼠烫伤实验研究  

Experimental Study of Topical Homemade Extract of Lithospermum Erythrorhizon Treating Scalded Rats

作　　者：王勇[1] 王双艳[1] 肖晏婴[1] 

机构地区：[1]湖北中医药大学附属襄阳医院药学部,湖北襄阳441000

出　　处：《中国药物警戒》2015年第6期330-331,共2页Chinese Journal of Pharmacovigilance

摘　　要：目的开展紫草浸膏治疗大鼠烫伤的药效学实验,明确其外用治疗烫伤的功能。方法选取SD大鼠60只,随机分成5组,恒温水浴烫伤大鼠右足造模,用软皮尺测量大鼠足趾周长,计算肿胀率。结果紫草高、低浓度组与对照组相比较有统计学差异(P<0.05)。结论自制紫草浸膏外用,对热水所致烫伤有一定的疗效,适宜临床推广应用。Objective To study the pharmacological effects of Lithospermum erythrorhizon on scalded rats in order to clarify its topical treatment function of burns. Methods 60 rats were randomly divided into 5 groups. We used the constant temperature water bath to manufacture rat burn model and measured the rat paw circumference with a soft tape measure. Foot swelling rate was evaluated with computer. Results Compared with the control group, there were significant differences in Lithospermum erythrorhizon high, low concentration group （P〈0.05）. Conolusion Homemade extract of Lithospermum erythrorhizon could treat hot water scaldand be suitable for clinical application.

关 键 词：紫草 浸膏 外用 烫伤 

分 类 号：R965[医药卫生—药理学]