110例痰热清注射剂不良反应分析  

Analysis of 110 Cases of Adverse Drug Reactions Induced by Tanreqing Injection

作　　者：于莉 邱召娟 谭喜莹 

机构地区：[1]南京中医药大学附属医院药学部,江苏南京210029

出　　处：《中国药物警戒》2015年第6期360-362,共3页Chinese Journal of Pharmacovigilance

基　　金：技部"重大新药创制"科技重大专项"中药上市后再评价关键技术研究"(2009ZX09502-030);江苏省中医院科技项目课题(Y11023)

摘　　要：目的 探讨痰热清注射液所致不良反应的规律、特点,促进临床合理用药。方法 对2008~2012年我院上报的与痰热清注射液相关的不良反应110例进行统计分析,分别记录不良反应发生时间,临床表现,痰热清注射液用法用量等情况。结果 大部分痰热清注射液致不良反应临床表现主要为皮肤及附件损害（n=75,62.5%）,且大多发生在用药60 min内。结论 临床医师和药师应重视痰热清注射液的不良反应,在用药过程中注意监护,尽可能减少不良反应发生。Objective To analyze the characters of ADR induced by Tanreqing injection so as to promote the rational use of the drugs. Methods 110 cases of ADRrelated to Tanreqing injection from 2008 to 2012 in Jiangsu Province Hospital of Traditional Chinese Medicine were analyzed statistically in terms of adverse reaction time, clinical manifestation, dosage and administration,etc. Results Most of the reports （n=75） involved both of the skin system and its appendages, accounting for 62.5%. Most of the cases occurred within 60 minute. Conclusion Doctors and pharmacists should pay more attention to the ADR of Tanreqing injection. The process of drug use should be monitored to reduce the incidence of ADR.

关 键 词：痰热清 药品不良反应 

分 类 号：R994.11[医药卫生—毒理学] R282[医药卫生—药学]