肥厚型梗阻性心肌病化学消融后急性期Tp-Te间期和Tp-Te/Q-T的变化  

The changes of Tp-Te Interval and Tp-Te/Q-T soon after chemical ablation in hypertrophic obstructive cardiomyopathy

作　　者：何玮[1] 陈长曦[1] 孙丽卿[1] 周浩[1] 李晟[1] 计光[1] 黄伟剑[1] 

机构地区：[1]温州医科大学附属第一医院心脏中心,325003

出　　处：《心电与循环》2015年第3期181-183,共3页Journal of Electrocardiology and Circulation

摘　　要：目的探讨肥厚型梗阻性心肌病(HOCM)化学消融后急性期Tp-Te间期和Tp-Te/Q-T的变化。方法 1 3例(男性3例,女性10例)HOCM患者行经皮酒精室间隔消融术治疗,分别于术前和术后行超声心动图和心电图检测。结果室间隔厚度和左心室质量指数消融术后较术前明显降低[分别为(18.08±2.02)mm、(20.77±2.39)mm;(186.56±58.30)g/m^2、(208.79±72.76)g/m^2],差异均有统计学意义(均P<0.05)。Tp-Te间期、Tp-Te/Q-T和Tp-Te/Q-Tc在消融术后24h及3~5d较术前降低[Tp-Te间期术前(136.15±7.12)ms,术后24h(129.23±9.76)ms,术后3~5d(128.08±10.11)ms;Tp-Te/Q-T术前0.32±0.03,术后24h 0.29±0.03,术后3~5d 0.29±0.03;Tp-Te/Q-Tc术前0.30±0.03,术后24h 0.27±0.02,术后3~5d 0.27±0.03],差异均有统计学意义(均P<0.05)。结论 HOCM室间隔消融术后急性期Tp-Te间期、Tp-Te/Q-T和Tp-Te/Q-Tc明显缩短。Objective To observe the changes of Tp-Te interval and Tp-Te/Q-T after chemical ablation in hypertrophic obstructive cardiomyopathy （HOCM）. Methods 13 patients （3 male, 10 female） with HOCM underwent percutaneous alcohol septal ablation. Echocardiography and electrocardiogram were performed before and after ablation Results Interventricular septum thickness and left ventricular mass index were significantly decreased from 20.77 ±2.39mm and 208.79± 72.76g/m^2 before to 18.08 ±2.02mm and 186.56 ±58.30g/m^2 after ablation, respectively （all P〈 0.05）. Tp-Te interval, Tp-Te/Q-T and Tp-Te/Q-Tc decreased significantly from 136.15±7.12ms, 0.32± 0.03 and 0.30 ± 0.03 before procedure to 129.23 ± 9.76ms, 0.29 ±0.03 and 0.27± 0.02 at 24h, to 128.08 ±10.11ms, 0.29 ± 0.03 and 0.27 ± 0.03 3 to 5 days after procedure, respectively （all P〈0.05 ）. Conclusion Tp-Te interval, Tp-Te/Q-T and Tp-Te/Q-Tc reduce significantly soon after septal ablation in HOCM.

关 键 词：肥厚型梗阻性心肌病 TP-TE间期 Tp-Te/Q-T Tp-Te/Q-Tc 化学消融 

分 类 号：R542.2[医药卫生—心血管疾病]