壮医莲花针背廊拔罐法对变应性鼻炎患者疗效及S-IgE的影响  

The effect of Zhuangyi-Lianhuazhen-Beilangbaguan on S-IgE expression and the treatment of allergic rhinitis

作　　者：杨培培[1] 冯纬纭[1] 黄贵华[1] 叶辉信[1] 黄卓燕[1] 李婕[1] 李艺[1] 黄瑾明[1] 

机构地区：[1]广西中医药大学第一附属医院耳鼻咽喉科,南宁530023

出　　处：《中国临床新医学》2015年第6期504-507,共4页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：国家自然科学基金资助项目(编号:81160465);广西自然科学基金资助项目(编号:2011GXNSFA018310);广西卫计委中医药科技专项课题(编号:GZKZ10-015)

摘　　要：目的探讨壮医莲花针背廊拔罐法治疗变应性鼻炎(AR)的有效性及对特异性IgE(S-IgE)表达的影响。方法从广西中医药大学附属医院耳鼻喉门诊及壮医门诊招募符合方案的AR患者60例,随机分为A、B两组,每组30例,分别用壮医莲花背廊拔罐和丙酸氟替卡松喷雾剂(喷鼻,1次/d)治疗;疗程均为10 d,停药1周后继续第2个疗程治疗,2个疗程后观察两组的疗效及对S-IgE的影响。结果 A组的疗效优于B组(P<0.05)。治疗后A、B组的S-IgE均明显低于治疗前(P<0.01),A组与B组比较差异有统计学意义(P<0.05)。研究过程中并未发现不良反应事件。结论壮医莲花针背廊拔罐法治疗AR疗效确切,其机制为抑制S-IgE的表达。Objective To study the effectiveness of using Zhuangyi-Lianhuazhen-Beilangbaguan for treating allergic rhinitis（ AR） .Methods Sixty patients with AR in our hospital were randomly divided into two groups（ Lianhuazhen group and Fluticasone group） .The Lianhuazhen group had a acupuncture using Lianhuazhen and Fluticasone group used Fluticasone nasal spray with a course of treatment of 10 days, and two courses in together.Another course of treatment was resumed after drug withdrawl for one week.The efficacy and S-IgE were compared between the two groups.Results The efficacy of Lianhuazhen group was more notable than that of Fluticasone group.After the treatment, the expression levels of S-IgE in the two groups were significantly lower than those in the two groups before the treatment （P〈0.05） and there were significant differences between the two groups（P〈0.05）;No adverse reaction was found in the patients of the two groups.Conclusion The therapy of Zhuangyi-Lianhuazhen-Beilangbaguan is ef-fective and the therapeutic mechanism of inhibiting S-IgE expression may be involved in.

关 键 词：变应性鼻炎 壮医莲花针背廊拔罐法 特异性IGE 临床研究 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]