2009-2013年北京市成年女性尿碘水平与甲状腺结节检出情况分析  

Survey on urinary iodine level and thyroid nodule among women in Beijing in 2009-2013

作　　者：李阳桦 张静波[2] 韩玉梅[2] 季建英[2] 陈硕[2] 王全意[1] 任海林[1] 杜丹[1] 刘博[1] 陈艳伟[1] 李爽[1] 黎新宇[1] 

机构地区：[1]北京市疾病预防控制中心传染病地方病控制所,北京100013 [2]北京市体检中心

出　　处：《中国预防医学杂志》2015年第6期410-413,共4页Chinese Preventive Medicine

基　　金：北京市自然科学基金资助项目(7123218)

摘　　要：目的了解北京市2009-2013年20~44岁女性尿碘水平与甲状腺结节检出情况,并分析两者的变化趋势。方法采用定量抽样的方法,每年在北京市每个区县分别采集不少于150名20~44岁女性的一次随机尿样测定尿碘含量,并分别在不同年龄组间及不同年份间进行秩和检验;同时收集2009-2013年在北京市体检中心进行甲状腺B超检查的全部20~44岁女性的甲状腺B超资料,并分别在不同年龄组间及不同年份间进行χ2检验。结果 2009-2013年北京市20~44岁女性人群尿碘中位数为190.10μg/L;人群尿碘水平基本呈随年份与年龄段增加逐渐下降的趋势;2009-2013年北京市20~44岁女性甲状腺结节检出率为31.84%（7 297/22 918）,且随着年份（趋势χ^2=468.595,P〈0.01）与年龄段（趋势χ^2=422.018,P〈0.01）增加呈逐渐上升趋势。结论 2009-2013年北京市20~44岁女性人群碘营养水平适宜。甲状腺结节检出率逐年上升,但与高碘营养水平无关。Objective To determine the iodine level in urine and the prevalence of thyroid nodules among women aged 20-44 years in Beijing from 2009 to 2013. Methods Urine samples were collected from at least150 women aged 20-44 years in Beijing once every year from 2009 to 2013to measure the urinary iodine level.Meanwhile,data of thyroid ultrasound were also collected from age matched women in Beijing Physical Examination Center during the same period.Chi-square test was used for statistical analysis. Results The median urinary iodine concentration was 190.10g/L among women aged 20-44 years in Beijing from 2009to2013,which decreased gradually along with year and age.The overall detection rate of thyroid nodule was31.84%（7 297/22 918）,which gradually increased along with year（trendχ^2=468.595,P〈0.01）and age（trendχ^2=422.018,P〈0.01）. Conclusions The iodine level among women aged 20-44 years in Beijing is in a normal range.Although the incidence of thyroid nodule goes up annually,this is not related to high iodine nutrition.

关 键 词：尿碘 甲状腺结节 妇女 

分 类 号：R581[医药卫生—内分泌]