中青年2型糖尿病患者睡眠状况及糖代谢状况调查  

Investigation of Circadian Rhythm and Glucose Metabolism in Young Patients with Type 2 Diabetes

作　　者：邓黎[1] 王颖[2] 王妙芳[1] 蒋友明[1] 王少波[1] 

机构地区：[1]东莞市厚街医院内分泌科,广东东莞523945 [2]中山大学附属第三医院综合ICU,广东广州510630

出　　处：《黑龙江医学》2015年第4期449-450,共2页Heilongjiang Medical Journal

基　　金：2012年度东莞市科技计划医疗卫生单位科研重点项目(2012105102025)

摘　　要：目的通过对中青年2型糖尿病昼夜节律及糖代谢状况的调查,了解该年龄阶段2型糖尿病患者的睡眠质量及睡眠障碍时的血糖调节状况。方法从厚街社区中青年2型糖尿病患者中随机抽取300名进行问卷调查,主要涉及匹兹堡睡眠质量指数及一般临床指标,并结合空腹及餐后2 h血糖、糖化血红蛋白结果进行统计分析。结果中青年2型糖尿病患者存在明显睡眠障碍,血糖波动大,胰岛素抵抗明显,血糖达标率低。结论中青年2型糖尿病患者本身存在睡眠时间短、睡眠延迟问题,睡眠障碍增加胰岛素抵抗,进而影响血糖调节。Objective To understand sleep quality and glucose regulation in young patients with type 2 diabetes by the investigation of circadian rhythm and glucose metabolism. Methods 300 samples were selected randomly from middle- aged and young patients with type2 diabetes in Houjie community. Indicators including Pittsburgh sleep quality index and general clinical indicators as well as fasting and postprandial 2 hours blood glucose and glycosylated hemoglobin were analyzed. Results Young and middle- aged patients with type 2 diabetes suffer from sleep disorders,great fluctuations in blood sugar,insulin resistance and blood sugar low success rate. Conclusion Middle- aged and young patients with type 2 diabetes suffer from short sleep time and sleep latency problems,and sleep disorders and these increase insulin resistance which,in turn,affect blood glucose regulation.

关 键 词：中青年2型糖尿病 昼夜节律 胰岛素抵抗 

分 类 号：R587.1[医药卫生—内分泌]