生物梅里埃 ATB STAPH 5葡萄球菌药敏试剂盒的局限性分析  

Limitation of Staphylococcus Spp Test Kit ATB STAPH 5 from BioMerieux in Clinical Applcation

作　　者：肖亚雄[1] 彭宇生[1] 王鹏[1] 黄忠团[1] 代小琴 

机构地区：[1]宜宾市第一人民医院检验科,四川宜宾644600

出　　处：《现代检验医学杂志》2015年第3期122-125,共4页Journal of Modern Laboratory Medicine

摘　　要：目的：分析探讨生物梅里埃产葡萄球菌药敏试剂盒 ATB STAPH 5在临床运用中存在的缺陷，并提出补救／解决方案。方法以 CLSI M100-S23提供的葡萄球菌对应抗生素拐点作为标准，对梅里埃药敏试剂盒 ATB STAPH 5抗生素覆盖情况与各抗生素拐点浓度进行对比分析。结果ATB STAPH5试剂盒不包括 CLSI 推荐的氯霉素类和恶唑烷酮类、脂肽类三类抗生素；ATB STAPH 5试剂盒提供的16种抗生素拐点均与 CLSI M100-S23推荐抗生素拐点不一致，从而可能导致临床药敏报告出现假敏感或假耐药的情况。结论在现行 CLSI 参考标准下，单独使用 ATB STAPH 5试剂盒进行葡萄球菌药敏试验将产生较大误差甚至错误，必须要其他药敏试验方法进行修正方可发出报告。Objective To study the limitation analysis of Staphylococcus spp Susceptibility Test Kit ATB STAPH 5 from Bi-oMerieux in clinical application and to propose remedy.Methods The coverage area and break point of antibiotics ATB STAPH 5 from BioMerieux were analysed by using CLSI M100-S23 as standard.Results The kit ATB STAPH 5 did not include chloromycetin,oxazolidinones and lipopeptide three antibiotics that were recommend by CLSI.The 16 kinds of antibi-otics break point in the kit ATB STAPH 5 were all not inconsistent or did not contain with the standard of CLSI M100-S23. It may lead to error drug sensitivity tests,false sensitive or false drug resistance.Conclusion Only using this kit ATB STAPH 5 for Staphylococcus spp ,it may occurre errors or mistakes.Other experiments must be corrected before the re-port.

关 键 词：生物梅里埃 药敏 葡萄球菌 局限性 

分 类 号：R446.5[医药卫生—诊断学]