高风险初产妇妊娠期糖尿病的筛查对新生儿的影响  

Effect of GDM screening among high-risk primiparous women on the neonates

作　　者：周晓莹[1] 郑冼华[1] 黄瑞玉[1] 周才[1] 赖有行[1] 

机构地区：[1]广东省妇幼保健院检验科,广东广州510000

出　　处：《中国妇幼保健》2015年第18期2925-2927,共3页Maternal and Child Health Care of China

摘　　要：目的：研究高风险初产妇妊娠期糖尿病（GDM）的筛查对妊娠结局和新生儿的影响。方法：选取2011年1月~2014年2月期间来该院进行产前检查并建档的300例高风险的初产妇作为研究对象,均在妊娠24~28周接受50 g葡萄糖负荷试验（GCT）和75 g葡萄糖耐量试验（OGTT）,并定期复查血糖。根据血糖水平将300例产妇分为观察组231例和对照组69例,比较两组产妇的剖宫产率、不良反应和并发症的发生率;比较两组新生儿的1 min和5 min Apgar评分;比较两组围产儿的并发症发生率。结果：观察组产妇的剖宫产率9.96%,不良反应发生率4.76%,并发症发生率4.33%;对照组产妇剖宫产率24.64%,不良反应发生率13.04%,并发症发生率15.94%,两组比较差异具有统计学意义（P〈0.05）。观察组新生儿1 min Apgar评分（9.5±0.2）分,围产儿并发症发生率4.33%;对照组新生儿1 min Apgar评分（9.0±0.3）分,围产儿并发症发生率14.71%,两组比较差异具有统计学意义（P〈0.05）。两组新生儿的5 min Apgar评分差异无统计学意义（P〉0.05）。结论：高风险产妇GDM的筛查对改善妊娠结局和新生儿的预后意义重大。Objective： To study the effect of gestational diabetes mellitus（ GDM） screening among high- risk primiparous women on pregnancy outcomes and the neonates. Methods： Three hundred GDM high- risk primiparous women receiving prenatal examination and establishing medical records in the hospital from January 2011 to February 2014 were selected,then 50 g glucose challenge test（ GCT） and75 g oral glucose tolerance test（ OGTT） were performed during 24- 28 gestational weeks,blood glucose levels were reexamined regularly.The primiparous women were divided into observation group（ 231 women） and control group（ 69 women） according to blood glucose levels;the cesarean section rates,the incidence rates of adverse reactions and complications in the two groups were compared; one- minute and five- minute Apgar scores of neonates in the two groups were compared; the incidence rates of complications of perinatal infants in the two groups were compared. Results： The cesarean section rate,the incidence rates of adverse reactions and complications in observation group were 9. 96%,4. 76%,and 4. 33%,respectively; the cesarean section rate,the incidence rates of adverse reactions and complications in control group were 24. 64%,13. 04%,and 15. 94%,respectively,there were statistically significant differences between the two groups（ P〈0. 05）. One- minute Apgar score and the incidence rate of complications of perinatal infants in observation group were（ 9. 5 ± 0. 2） and4. 33%,respectively; one- minute Apgar score and the incidence rate of complications of perinatal infants in control group were（ 9. 0 ±0. 3） and 14. 71%,respectively,there were statistically significant differences between the two groups（ P〉0. 05）. There was no statistically significant difference in five- minute Apgar score of neonates between the two groups（ P〈0. 05）. Conclusion： GDM screening among high- risk primiparous women is of great significance for improving pregnancy outcomes and prognosis of the neonates.

关 键 词：初产妇 妊娠期糖尿病 糖耐量异常 妊娠结局 新生儿 

分 类 号：R714[医药卫生—妇产科学]