孕宫1号联合甲氨蝶呤、米非司酮保守治疗异位妊娠的有效性与安全性研究  

Study on the efficacy and safety of pregnant house No.1 combined with methotrexate,mifepristone in conservative treatment of ectopic pregnancy

作　　者：李雪萍[1] 罗菊玉 

机构地区：[1]黔东南民族职业技术学院妇产科教研室,贵州凯里556000 [2]黔东南州人民医院妇科

出　　处：《中国妇幼保健》2015年第18期3012-3014,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨孕宫1号联合西药保守治疗异位妊娠的有效性与安全性。方法:选择61例异位妊娠患者为研究对象,采用随机数字表法分为对照组(30例)和观察组(31例),对照组采用甲氨蝶呤(MTX)肌注+米非司酮口服治疗,观察组在上述基础上联合中药方剂孕宫1号,比较两组治疗有效性与安全性。结果:观察组治愈率(90.32%)明显高于对照组(P<0.05);阴道流血、腹痛、包块消失、血β-h GG转阴、住院时间、不良反应发生率均明显低于对照组(P<0.05)。结论:孕宫1号辅助西药保守治疗可有效缓解患者临床症状,提高治疗效果,降低不良反应发生率。Objective： To explore the efficacy and safety of pregnant house No. 1 combined with western medicine in conservative treatment of ectopic pregnancy. Methods： Sixty- one patients with ectopic pregnancy were divided into control group（ 30 patients） and observation group（ 31 patients） according to random number table; the patients in control group were treated with intramuscular injection of methotrexate and oral administration of mifepristone; while the patients in observation group were treated with intramuscular injection of methotrexate,oral administration of mifepristone,and pregnant house No. 1; the efficacies and safeties in the two groups were compared. Results： The cure rate in observation group was 90. 32%,which was statistically significantly higher than that in control group（ P〈0. 05）;the incidence rates of vaginal bleeding and abdominal pain,lumps disappear,conversion rate of blood β- human chorionic gonadotropin（ β- HGG）,hospitalization time,and the incidence rate of adverse reactions in observation group were statistically significantly lower than those in control group（ P〈0. 05）. Conclusion： Pregnant house No. 1 combined with western medicine can effectively relieve clinical symptoms,improve treatment effect,reduce the incidence rate of adverse reactions.

关 键 词：异位妊娠 安全性 孕宫1号 保守治疗 

分 类 号：R714.22[医药卫生—妇产科学]